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Keywords: Presomitic mesoderm
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Journal: Development
Development (2017) 144 (20): 3808–3818.
Published: 15 October 2017
... and of the transcriptional co-activator SAGA, is required for the assembly of these complexes in the mouse embryo. We performed Taf10 conditional deletions during mesoderm development and show that Taf10 loss in the presomitic mesoderm (PSM) does not prevent cyclic gene transcription or PSM segmental patterning, whereas...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (16): 2982–2993.
Published: 15 August 2017
...Richa Sharma; Maxwell E. R. Shafer; Eric Bareke; Mathieu Tremblay; Jacek Majewski; Maxime Bouchard ABSTRACT Caudal somites are generated from a pool of progenitor cells located in the tailbud region. These progenitor cells form the presomitic mesoderm that gradually differentiates into somites...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (11): 2260–2270.
Published: 1 June 2014
... and presomitic mesoderm. In the presence of RA, RARγ2 serves as an activator, facilitating somite differentiation. Treatment with an RARγ-selective inverse agonist (NRX205099) or overexpression of dominant-negative RARγ increases the expression of posterior Hox genes and that of marker genes for presomitic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (2): 277–287.
Published: 15 January 2012
...Laurent Yvernogeau; Gwenola Auda-Boucher; Josiane Fontaine-Perus We have combined the use of mouse genetic strains and the mouse-into-chicken chimera system to determine precisely the sequence of forelimb colonization by presomitic mesoderm (PSM)-derived myoblasts and angioblasts, and the possible...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (9): 1515–1522.
Published: 1 May 2010
..., suggesting the importance of the Notch on/off state for boundary formation. However, a recent study has shown that mouse embryos expressing Notch-intracellular domain (NICD) throughout the presomitic mesoderm (PSM) can still form more than ten somites, indicating that the NICD on/off state is dispensable...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (15): 2555–2562.
Published: 1 August 2008
...Masayuki Oginuma; Yasutaka Niwa; Deborah L. Chapman; Yumiko Saga The metameric structures in vertebrates are based on the periodicity of the somites that are formed one by one from the anterior end of the presomitic mesoderm (PSM). The timing and spacing of somitogenesis are regulated...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2007) 134 (8): 1561–1569.
Published: 15 April 2007
.... Huppert, S. S., Ilagan, M. X., De Strooper, B. and Kopan, R. ( 2005 ). Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation. Dev. Cell 8 , 677 -688. Iulianella, A., Melton, K. R. and Trainor, P. A. ( 2003...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (20): 4797–4807.
Published: 15 October 2003
... , but not Myf5 expression;however, we show that the source of the Wnt signal is intrinsic to the mesoderm. Gain- and loss-of-function experiments indicate that Wnt5b ,which is expressed in the presomitic mesoderm, represents the MyoD -activating cue. Despite Wnt5b expression in the presomitic mesoderm, MyoD...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1997) 124 (11): 2245–2254.
Published: 1 June 1997
... Notch hindbrain presomitic mesoderm neurogenesis mouse Drosophila Intercellular signaling is a fundamental feature underlying the establishment of pattern during embryonic development ( Jessell and Melton, 1992 ). Theoretical models predict that an important aspect of embryonic...
Journal Articles
Journal Articles
Journal: Development
Development (1986) 92 (1): 269–285.
Published: 1 March 1986
...P. P. L. Tam ABSTRACT Consistently six to seven somites were formed in explants of presomitic mesoderm of 8·5-day to 11·5-day mouse embryos and this number correlated well with the number of somitomeres previously identified in the same tissue by stereo SEM (Tam, Meier & Jacobson, 1982...