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Keywords: Polyploidy
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Journal Articles
Journal: Development
Development (2021) 148 (8): dev197343.
Published: 26 April 2021
... - 428 . Duncan , A. W. ( 2013 ). Aneuploidy, polyploidy and ploidy reversal in the liver . Semin. Cell Dev. Biol. 24 , 347 - 356 . 10.1016/j.semcdb.2013.01.003 Finkel , T. and Holbrook , N. J. ( 2000 ). Oxidants, oxidative stress and the biology of ageing . Nature...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (15): dev173005.
Published: 2 August 2019
...Janelle Grendler; Sara Lowgren; Monique Mills; Vicki P. Losick ABSTRACT Tissue repair usually requires either polyploid cell growth or cell division, but the molecular mechanism promoting polyploidy and limiting cell division remains poorly understood. Here, we find that injury to the adult...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (24): 4288–4298.
Published: 15 December 2015
... of a variety of tissues. An important example is endoreplication, in which endocycling cells alternate between G and S phase without intervening mitosis or cytokinesis, resulting in polyploidy. Although significantly different from the canonical cell cycle, endocycles use regulatory pathways that also function...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (18): 3551–3560.
Published: 15 September 2014
... Endocycle Polyploidy Multipolar Aneuploidy Centrosome Drosophila In many post-mitotic tissues, continued growth and development is achieved by a cell cycle modification known as the endocycle. In diverse tissues, including the human trophoblast lineage, endocycles alternate DNA synthesis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (21): 4777–4787.
Published: 1 November 2005
... and develop giant bristles that may reflect their high degree of ploidy. * Authors for correspondence (e-mail: mb2@mrc-lmb.cam.ac.uk and kkhanson@mrc-lmb.cam.ac.uk ) 24 8 2005 ©2005. 2005 Chromosomal passenger complex Mitotic spindle Polyploidy Borealin/Dasra Tissue repair...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (10): 2377–2388.
Published: 15 May 2005
... VI; ph3, phospho-histone H3. Scale bar: 70 μm for A-C,H; 80μm for D-G. Inner ear Cochlea Vestibular organ Hair cell Proliferation Differentiation Apoptosis Cell cycle Mitosis Polyploidy Rb ( Rb1 ) p21 ( Cdkn1a ) Mouse The auditory sensory epithelium of the cochlea...