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Keywords: Pituitary
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Journal Articles
Journal: Development
Development (2019) 146 (23): dev177790.
Published: 2 December 2019
... enteropathy characterized by hypoproteinemia, hypoalbuminemia, and hypertriglyceridemia . Cell Mol. Gastroenterol. Hepatol.   1 , 381 - 394.e387 . 10.1016/j.jcmgh.2015.05.001 Farquhar , M. G. ( 1961 ). Fine structure and function in capillaries of the anterior pituitary gland . Angiology   12...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2017) 144 (19): 3521–3532.
Published: 1 October 2017
..., adenohypophyseal placode precursors differ from the remaining preplacodal ectoderm as they are clustered at the midline, resembling other midline structures important for maintaining the bilateral organization of the neural tube. Adhesion Cell movement Midline Pituitary Chick RNA-seq Sp8...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (18): 3289–3302.
Published: 15 September 2017
... of pituitary cell types. Here, we have used a genetic approach to demonstrate that activation of the SHH pathway is necessary to induce LHX3 + /LHX4 + RP identity in mouse embryos. First, we show that conditional deletion of Shh in the anterior hypothalamus results in a fully penetrant phenotype characterised...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (13): 2376–2388.
Published: 1 July 2016
...Sam Goldsmith; Robin Lovell-Badge; Karine Rizzoti Sox2 mutations are associated with pituitary hormone deficiencies and the protein is required for pituitary progenitor proliferation, but its function has not been well characterized in this context. SOX2 is known to activate expression of Six6...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (1): 75–85.
Published: 1 January 2011
... patterning. Our phenotypic analysis suggests that Boc is required as a positive regulator of Hh signaling in the spinal cord, hypothalamus, pituitary, somites and upper jaw, but that Boc might negatively regulate Hh signals in the lower jaw. This study reveals a role for Boc in ventral CNS cells that receive...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (6): 1079–1089.
Published: 15 March 2006
... a transient phase of cell death, which affects most, but not all adenohypophyseal cells. Surviving cells form a smaller pituitary rudiment,lack expression of specific adenohypophyseal marker genes ( pit1,neurod ), while expressing others ( lim3, pitx3 ), and display an ultrastructure reminiscent of precursor...
Journal Articles
Journal: Development
Development (2006) 133 (2): 351–361.
Published: 15 January 2006
... ) * These authors contributed equally to this work 9 11 2005 © 2006. 2006 Retinoids Forebrain development Eye development Neural crest Telencephalon Diencephalon Optic vesicle Pituitary Sonic hedgehog FGF Mouse Aldh1a2 The embryonic forebrain...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3681–3692.
Published: 1 August 2004
...Wiebke Herzog; Carmen Sonntag; Sophia von der Hardt; Henry H. Roehl; Zoltan M. Varga; Matthias Hammerschmidt The pituitary gland consists of two major parts: the neurohypophysis, which is of neural origin; and the adenohypophysis, which is of non-neural ectodermal origin. Development...
Journal Articles
Journal: Development
Development (2001) 128 (24): 5189–5199.
Published: 15 December 2001
... of vertebrate species. Its role in pituitary development has been documented through loss-of-function studies in the mouse. A homozygous missense point mutation resulting in a single amino acid substitution, Arg160Cys (R160C), is associated with a heritable form of the human condition of septo-optic dysplasia...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3497–3509.
Published: 15 September 2001
... a zebrafish ortholog of Smoothened that transduces Hedgehog signals. Zebrafish smoothened is expressed maternally and zygotically and supports specification of motoneurons, pituitary cells and ventral forebrain. We propose that smoothened is required for induction of lateral floor plate and a subpopulation...