... and chemical inhibitor analyses in zebrafish show that Bmp signaling to the endoderm is required for proper endoderm morphogenesis and subsequent craniofacial development. Bmp signaling Pharyngeal pouches Endoderm morphogenesis Fgf signaling Zebrafish Formation of the adult body plan requires...

...Chong Pyo Choe; J. Gage Crump Branching morphogenesis depends on the precise temporal and spatial control of epithelial dynamics. In the vertebrate head, endodermal branches, called pharyngeal pouches, form through the transient stratification, collective migration and reorganization of epithelial...

...Chong Pyo Choe; J. Gage Crump The pharyngeal pouches are a segmental series of epithelial structures that organize the embryonic vertebrate face. In mice and zebrafish that carry mutations in homologs of the DiGeorge syndrome gene TBX1 , a lack of pouches correlates with severe craniofacial defects...

...-mail: draible@u.washington.edu ) 22 4 2005 ©2005. 2005 Fgf3 Foxi1 Epibranchial placodes Cranial ganglia Endoderm Pharyngeal pouches Placode induction Neurogenesis Neurogenic cranial placodes are transient ectodermal thickenings that form at the border of the neural plate...

... movements in living embryos, we show that contact between pharyngeal pouches and the surface ectoderm coincides with the onset of neurogenesis in epibranchial placodes. By genetic ablation and reintroduction of endoderm by cell transplantation, we show that these contacts promote neurogenesis. Using...

...Robyn Quinlan; Paul Martin; Anthony Graham The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches. These are structures of considerable importance; they are required to segregate the mesenchymal populations of each arch and to induce the formation of arch components...

..., respectively; B1-2, fused first and second branchial arches; D,dorsal aorta; H, heart; P1, first pharyngeal pouch. White arrowhead (A)indicates the first branchial cleft. Scale bar in F: 200 μm in E,F. Fig. 2. Effects on branchial arch development of the RARβ agonist BMS453. External (A-D) and histological...