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Keywords: Patterning
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Journal Articles
Journal: Development
Development dev.200539.
Published: 14 July 2022
...Qianlin Ye; Arshia Bhojwani; Jimmy K. Hu During craniofacial development, the oral epithelium begins as a morphologically homogeneous tissue that gives rise to locally complex structures, including the teeth, salivary glands, and taste buds. How the epithelium is initially patterned and specified...
Journal Articles
Journal: Development
Development (2022) 149 (12): dev200226.
Published: 23 June 2022
... patterning of cell fate decisions. SynNotch technology has been used for monitoring cell-cell interactions, generating synthetic patterns, generating synthetic morphogen gradients, inducing contact-mediated gene editing and generating custom antigen receptor T-cells ( Cho et al., 2018 ; Choe et al...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (7): dev200125.
Published: 30 March 2022
... at an upstream step in patterning the AP axis. Double RNAi experiments and eye regeneration assays suggest src-1 can act in parallel to at least some Wnt and FGFRL factors. Co-inhibition of src-1 with other posterior-promoting factors led to dramatic patterning changes and a reprogramming of Wnt/FGFRLs...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2022) 149 (7): dev200410.
Published: 30 March 2022
..., but during leaf development it regulates the development of distinct cell types; bundle-sheath in Arabidopsis and mesophyll in maize. In rice, SCR is implicated in stomatal patterning, but it is unknown whether this function is additional to a role in inner leaf patterning. Here, we demonstrate that two...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (5): dev199632.
Published: 9 March 2022
... this model has not been tested. Some insects, e.g. Nasonia vitripennis and Apis mellifera segment progressively, a pattern not examined in previous studies of this segmentation model, producing stripes at different times progressively through the embryo, but not from a segment addition zone. Here, we aim...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (1): dev200140.
Published: 13 January 2022
...Esther Jeong Yoon Kim; Lydia Sorokin; Takashi Hiiragi ABSTRACT Development entails patterned emergence of diverse cell types within the embryo. In mammals, cells positioned inside the embryo give rise to the inner cell mass (ICM), which eventually forms the embryo itself. Yet, the molecular basis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (15): dev186387.
Published: 3 August 2021
... unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Summary: This Primer introduces micropatterning as a tool to study development and discusses what we have learnt so far with this technique. Microfabrication Patterning Self...
Journal Articles
Journal: Development
Development (2021) 148 (14): dev193268.
Published: 19 July 2021
... at the single-cell level and establishment of patterns at the tissue-wide level. Here, we emphasize that the general principles of embryonic development and tissue homeostasis are similar, and argue that interactions between these disciplines will be beneficial for both research fields. Tight regulation...
Journal Articles
Journal: Development
Development (2021) 148 (14): dev199497.
Published: 12 July 2021
... at large. Leading scientists from a range of disciplines, including developmental biology, physics, chemistry and computer science, covered a gamut of topics from the principles of cell and tissue organization, patterning and gene regulatory networks, to synthetic approaches for exploring evolutionary...
Journal Articles
Journal: Development
Development (2021) 148 (4): dev193227.
Published: 16 February 2021
...: A spatially restricted program of retinoic acid production and degradation is established by Zic1 and its targets Cyp26c1 and Pitx2c to pattern the precursor region for all paired sensory organs. Retinoic acid Placode Xenopus Degradation Patterning Paired sensory organs in vertebrates...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (22): dev190173.
Published: 30 November 2020
... established markers of its secretory function and genes implicated in its development and maintenance ( Lmx1a and Otx2 ); (2) shows a perturbed expression of signaling pathways previously unexplored in hChP patterning (Wnt3); and (3) displays a lack of multiciliated epithelial cells and a profound...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (22): dev194761.
Published: 23 November 2020
.... The posterior Hox group expanded in the deuterostome clade and patterns caudal and distal structures. We aimed to address how similar Hox TFs diverge to induce different positional identities. We studied Hox TF DNA-binding and regulatory activity during an in vitro motor neuron differentiation system...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (20): dev190553.
Published: 29 October 2020
...Andrew D. Economou; Nicholas A. M. Monk; Jeremy B. A. Green ABSTRACT Periodic patterning is widespread in development and can be modelled by reaction-diffusion (RD) processes. However, minimal two-component RD descriptions are vastly simpler than the multi-molecular events that actually occur...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (20): dev193888.
Published: 26 October 2020
.../j.ydbio.2013.09.030 Cooper , F. , Gentsch , G. E. , Mitter , R. , Bouissou , C. , Healy , L. , Smith , J. C. and Bernardo , A. S. ( 2020 ). Rostrocaudal patterning and neural crest differentiation of human pre-neural spinal cord progenitors in vitro . bioRxiv , 1...
Journal Articles
Journal: Development
Development (2020) 147 (15): dev192070.
Published: 7 August 2020
... (ADHs) or retinol dehydrogenases (RDHs); and oxidation of retinaldehyde into RA by aldehyde dehydrogenases family 1, subfamily A (ALDH1as), such as ALDH1a1, ALDH1a2 and ALDH1a3. Levels of RA in tissues are regulated by spatiotemporal expression patterns of genes encoding RA-synthesizing and -degrading...
Journal Articles
Journal: Development
Development (2020) 147 (9): dev188573.
Published: 4 May 2020
... and modify their complex architectures? Several talks grappled with these questions, which are central to organogenesis, homeostasis and disease. Arthur Lander (University of California, Irvine, USA) noted that embryos are highly robust and that sizes and patterns are specified with remarkable precision...
Journal Articles
Journal: Development
Development (2020) 147 (4): dev182899.
Published: 20 February 2020
... types, but largely lacking complex developmental patterning, which evolved independently in different bilaterian clades during the Cambrian Explosion. * Author for correspondence ( erwind@si.edu ) Competing interests The authors declare no competing or financial interests. © 2020...
Journal Articles
Journal: Development
Development (2019) 146 (24): dev181107.
Published: 16 December 2019
....   259 , 34 - 47 . 10.1016/S0012-1606(03)00177-5 Mishima , N. and Tomarev , S. ( 1998 ). Chicken Eyes absent 2 gene: isolation and expression pattern during development . Int. J. Dev. Biol.   42 , 1109 - 1115 . Mundell , N. A. and Labosky , P. A. ( 2011 ). Neural...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (22): dev182154.
Published: 25 November 2019
... in discrete domains along the dorsal-ventral and anterior-posterior axes of the embryonic spinal cord. This organization arises in response to morphogen gradients acting upstream of a gene regulatory network, the architecture of which determines the spatial and temporal pattern of gene expression. In recent...
Journal Articles
Journal: Development
Development (2019) 146 (18): dev170480.
Published: 25 September 2019
...Erik Clark; Andrew D. Peel; Michael Akam ABSTRACT There is now compelling evidence that many arthropods pattern their segments using a clock-and-wavefront mechanism, analogous to that operating during vertebrate somitogenesis. In this Review, we discuss how the arthropod segmentation clock...