... in palatogenesis through the control of ciliary homeostasis, which establishes a new mechanism for Wnt-regulated craniofacial morphogenesis. Balanced cellular activities, such as proliferation and apoptosis, are crucial for mesenchymal cells during soft palate development. In order to determine why soft...

...Kendall J. Lough; Danielle C. Spitzer; Abby J. Bergman; Jessica J. Wu; Kevin M. Byrd; Scott E. Williams; Sally Dunwoodie; John Wallingford ABSTRACT Cleft palate (CP), one of the most common congenital conditions, arises from failures in secondary palatogenesis during embryonic development. Several...

... Wnt signaling and led to the growth and fusion of palatal shelves, as marked by an increase in cell proliferation and osteogenesis in utero , while other organ defects were not corrected. This work underscores the importance of Pax9-dependent Wnt signaling in palatogenesis and suggests...

...Jeffrey O. Bush; Rulang Jiang Mammalian palatogenesis is a highly regulated morphogenetic process during which the embryonic primary and secondary palatal shelves develop as outgrowths from the medial nasal and maxillary prominences, respectively, remodel and fuse to form the intact roof...

... ). Regional heterogeneity in the developing palate: morphological and molecular evidence for normal and abnormal palatogenesis. Congenit. Anom. 46 , 49 -54. Park, W. Y., Miranda, B., Lebeche, D., Hashimoto, G. and Cardoso, W. V. ( 1998 ). FGF-10 is a chemotactic factor for distal epithelial buds...

... a crucial, cell-autonomous role in regulating the fate of CNC cells during palatogenesis. During skull development, disruption of TGFβ signaling in the CNC severely impairs cell proliferation in the dura mater, consequently resulting in calvaria agenesis. We provide in vivo evidence that TGFβ signaling...

... kératinocytes of the embryonic skin at a time when the rate of kératinocyte cell division would be slowing. * To whom correspondence should be addressed © 1990 by Company of Biologists 1990 TGF beta in situ hybridisation mouse embryo palatogenesis The murine secondary palate...