... placode Genetic network Paired Fibroblast growth factor forkhead distal-less msxC Pax proteins are key regulators of developmental processes including specification, differentiation, growth, survival, migration and morphogenesis( Chi and Epstein, 2002 ; Dahl et al., 1997 ; Mansouri...

...Lei Xue; Markus Noll The Drosophila Pax gene paired encodes a transcription factor that is required for the activation of segment-polarity genes and proper segmentation of the larval cuticle, postembryonic viability and male fertility. We show that paired executes a dual role in the development...

... cellularization. Its establishment requires wild-type paired activity and thus indirectly requires bicoid . It occurs in a region of the embryo that ultimately gives rise to the cephalic furrow and may account for the effect of paired on that structure during gastrulation. Our results therefore suggest a link...

...Gregory K. Davis; Carlos A. Jaramillo; Nipam H. Patel Pair-rule genes were identified and named for their role in segmentation in embryos of the long germ insect Drosophila . Among short germ insects these genes exhibit variable expression patterns during segmentation and thus are likely to play...

...Lei Xue; Xuelin Li; Markus Noll ABSTRACT The Drosophila segmentation gene paired , whose product is homologous to the Drosophila Gooseberry and mammalian Pax3 proteins, has three general functions: proper development of the larval cuticle, survival to adulthood and male fertility. Both DNA-binding...

...Pawel Miskiewicz; David Morrissey; Yu Lan; Lakshmi Raj; Steven Kessler; Miki Fujioka; Tadaatsu Gotos; Michael Weir ABSTRACT Drosophila paired , a homolog of mammalian Pax-3 , is key to the coordinated regulation of segment-polarity genes during embryogenesis. The paired gene and its homologs...

...Miki Fujioka; Pawel Miskiewicz; Lakshmi Raj; Alyssa A. Gulledge; Michael Weir; Tadaatsu Goto ABSTRACT The even-skipped ( eve ) pair-rule gene plays a key role in the establishment of the anterior-posterior segmental pattern of the Drosophila embryo. The continuously changing pattern of eve...

...Claudio Bertuccioli; Laurent Fasano; Susie Jun; Sheng Wang; Guojun Sheng; Claude Desplan ABSTRACT The Drosophila pair-rule gene paired is required for the correct expression of the segment polarity genes wingless, engrailed and gooseberry . It encodes a protein containing three conserved motifs...