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Keywords: PGCs
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Journal Articles
Journal: Development
Development (2021) 148 (20): dev199732.
Published: 19 October 2021
.... Highlighted Article: YAP, an intracellular mediator of the Hippo signaling pathway, establishes epiblast competency for germ cell differentiation through activation of the WNT pathway. EpiSCs PGCs Hippo pathway Pluripotent stem cells Mouse European Research Council http://dx.doi.org...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (1): dev155978.
Published: 8 January 2018
...Amanda M. Butler; Dawn A. Owens; Lingyu Wang; Mary Lou King ABSTRACT Xenopus primordial germ cells (PGCs) are determined by the presence of maternally derived germ plasm. Germ plasm components both protect PGCs from somatic differentiation and begin a unique gene expression program. Segregation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (2): 292–304.
Published: 15 January 2017
... of maternal vegetally localized mRNAs show that sox7 plays a novel and important role in primordial germ cell (PGC) development and that ephrinB1 ( efnb1 ) is required for proper PGC migration. We propose potential pathways operating at the vegetal pole that highlight where future investigations might be most...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (23): 4457–4467.
Published: 1 December 2014
...Yasuhisa Matsui; Asuka Takehara; Yuko Tokitake; Makiko Ikeda; Yuka Obara; Yuiko Morita-Fujimura; Tohru Kimura; Toru Nakano Primordial germ cells (PGCs) are undifferentiated germ cells in embryos, the fate of which is to become gametes; however, mouse PGCs can easily be reprogrammed into pluripotent...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (14): 2892–2903.
Published: 15 July 2013
... of epimutations. Notably, primordial germ cells (PGCs) erase genome-wide DNA methylation and H3K9 dimethylation marks in a stepwise manner during migration and gonadal periods. In this study, we profiled DNA and histone methylation on transposable elements during PGC development, and examined the role of DNA...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (8): 1476–1486.
Published: 15 April 2012
...Fangfang Lai; Amar Singh; Mary Lou King Nanos is expressed in multipotent cells, stem cells and primordial germ cells (PGCs) of organisms as diverse as jellyfish and humans. It functions together with Pumilio to translationally repress targeted mRNAs. Here we show by loss-of-function experiments...
Journal Articles
Journal: Development
Development (2003) 130 (18): 4279–4286.
Published: 15 September 2003
..., A. H., Kuroda, M., Taniuchi, I. and Littman, D. R. ( 1998 ). Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393 , 595 -599. We thank Gord Fishell for support with microscopy and dissection; Dan Marmer for his assistance in sorting PGCs...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (1985) 90 (1): 251–265.
Published: 1 December 1985
...Yasuko Akita; Masami Wakahara Correlation of the number of primordial germ cells (PGCs) at stage 47 with the amount of germ plasm at the 8-cell stage and with the number of the germ-plasm-containing cells (GPCCs) was analysed using two different laboratory-raised colonies of Xenopus laevis , HD...