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Keywords: Overexpression
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Journal Articles
Journal: Development
Development (2015) 142 (3): 597–606.
Published: 1 February 2015
... here enables mosaic screens in the context of gene knockdown or overexpression by automatically generating a reliable ratio of mutant to wild-type tissue in a developmentally controlled manner. CoinFLP-Gal4 generates mosaic tissues composed of clones of which only a subset expresses Gal4. CoinFLP...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (11): 2434–2442.
Published: 1 June 2013
...Johannes Bischof; Mikael Björklund; Edy Furger; Claus Schertel; Jussi Taipale; Konrad Basler Overexpression screens are used to explore gene functions in Drosophila , but this strategy suffers from the lack of comprehensive and systematic fly strain collections and efficient methods for generating...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (21): 3585–3595.
Published: 1 November 2009
.... * Author for correspondence( Elizabeth.jones@warwick.ac.uk ) 1 9 2009 © 2009. 2009 Overexpression of notch-ICD mRNA in embryos harvested at stage 41 and whole-mount antibody stained with 3G8, which detects nephrostomes and proximal pronephric tubules, and 4A6, which detects intermediate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (15): 2511–2520.
Published: 1 August 2008
...Stephen J. Gaunt; Deborah Drage; Richard C. Trubshaw To investigate the link between Cdx protein concentration and axial patterning in embryos, we made lines of mice OE1, OE2 and OE4 that overexpress each of the Cdx genes Cdx1 , Cdx2 and Cdx4 ,respectively. The lines carry Cdx transgenes under...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (7): 1311–1322.
Published: 1 April 2007
... for the complex role of Pax6 in mammalian corticogenesis. * Author for correspondence (e-mail: astoyko@gwdg.de ) 17 1 2007 © 2007. 2007 Corticogenesis Cre/ loxP Overexpression Pax6 Pax6-5a Progenitor Apoptosis Mouse Pax6 is an evolutionarily conserved transcription...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (3): 545–555.
Published: 1 February 2007
... of late cortical progenitors specifically, and analysis of PAX77↔wild-type chimeras indicates that the defect is cell autonomous. We analyzed cortical arealization in PAX77 mice and found that, whereas the loss of Pax6 shifts caudal cortical areas rostrally, Pax6 overexpression at levels predicted...
Includes: Supplementary data