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Keywords: Otic placode
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Journal Articles
Journal: Development
Development (2018) 145 (4): dev160325.
Published: 21 February 2018
... to promoter regions of actively transcribed genes to control H3K9 demethylation. Chick embryo Epigenetic marks Histone modification Otic placode Transcription factor In the developing embryo, multipotent progenitors are able to maintain their identity and gene expression programmes despite...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (2): 245–257.
Published: 15 January 2012
.... References Abello G. , Khatri S. , Radosevic M. , Scotting P. J. , Giraldez F. , Alsina B. ( 2010 ). Independent regulation of Sox3 and Lmx1b by FGF and BMP signaling influences the neurogenic and non-neurogenic domains in the chick otic placode . Dev. Biol. 339 , 166...
Journal Articles
Journal: Development
Development (2008) 135 (13): 2251–2261.
Published: 1 July 2008
...Chathurani S. Jayasena; Takahiro Ohyama; Neil Segil; Andrew K. Groves The inner ear derives from a patch of ectoderm defined by expression of the transcription factor Pax2. We recently showed that this Pax2 + ectoderm gives rise not only to the otic placode but also to the surrounding cranial...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (13): 2449–2458.
Published: 1 July 2007
.... A.,Postlethwait. P. and Westerfield, M. ( 2003 ). Fgf3 and Fgf8 dependent and independent transcription factors are required for otic placode specification. Development 130 , 2213 -2224. Lombardo, A., Isaacs, H. V. and Slack, J. M. ( 1998 ). Expression and functions of FGF-3 in Xenopus development. Int...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (12): 2369–2378.
Published: 15 June 2007
...-mail: n.daudet@ucl.ac.uk ) * These authors contributed equally to this work 26 3 2007 © 2007. 2007 Notch signalling Serrate Delta Chick embryo Inner ear Otic placode Neuroblasts Hair cell Lateral inhibition Lateral induction The vertebrate inner ear...
Journal Articles
Journal: Development
Development (2006) 133 (5): 877–887.
Published: 1 March 2006
... identified that mark such a`pre-placodal' domain. However, the functional significance of this pre-placodal domain is still unclear. In the present study, we show that Fgf signaling is necessary and sufficient to directly induce some, but not all,markers of the otic placode in ectoderm taken from the pre...
Journal Articles
Journal: Development
Development (2006) 133 (5): 865–875.
Published: 1 March 2006
...Takahiro Ohyama; Othman A. Mohamed; Makoto M. Taketo; Daniel Dufort; Andrew K. Groves The otic placode, the anlagen of the inner ear, develops from an ectodermal field characterized by expression of the transcription factor Pax2 . Previous fate mapping studies suggest that these Pax2 + cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (2): 371–382.
Published: 15 January 2005
... at the midbrain-hindbrain junction and in the CNS; this expression pattern has been conserved from zebrafish to mouse( Pfeffer et al., 1998 ). Pax2 and Pax8 homologs are also expressed in the otic placode and pronephros in these species( Pfeffer et al., 1998 ; Plachov et al., 1990 ). Recent evidence has...
Journal Articles
Journal: Development
Development (2004) 131 (20): 5091–5102.
Published: 15 October 2004
...Stefan Hans; Dong Liu; Monte Westerfield The vertebrate inner ear arises from an ectodermal thickening, the otic placode, that forms adjacent to the presumptive hindbrain. Previous studies have suggested that competent ectodermal cells respond to Fgf signals from adjacent tissues and express two...
Journal Articles
Journal: Development
Development (2004) 131 (8): 1755–1763.
Published: 15 April 2004
...Natasha Saint-Germain; Young-Hoon Lee; Yanhui Zhang; Thomas D. Sargent; Jean-Pierre Saint-Jeannet The vertebrate inner ear develops from a thickening of the embryonic ectoderm, adjacent to the hindbrain, known as the otic placode. All components of the inner ear derive from the embryonic otic...
Journal Articles
Journal: Development
Development (2003) 130 (11): 2543–2554.
Published: 1 June 2003
...Robert M. Nissen; Jizhou Yan; Adam Amsterdam; Nancy Hopkins; Shawn M. Burgess We identified four insertional alleles of foxi one ( foo ),an embryonic lethal mutation in zebrafish that displays defects in both otic placode and the jaw. In foo/foo embryos the otic placode is split into two smaller...
Journal Articles
Journal: Development
Development (2003) 130 (5): 929–940.
Published: 1 March 2003
...Keely S. Solomon; Tetsuhiro Kudoh; Igor B. Dawid; Andreas Fritz The otic placode is a transient embryonic structure that gives rise to the inner ear. Although inductive signals for otic placode formation have been characterized, less is known about the molecules that respond to these signals within...
Journal Articles
Journal: Development
Development (2002) 129 (13): 3127–3136.
Published: 1 July 2002
... in concert and their importance in placode formation is only revealed by inactivating both paralogs. *Author for correspondence (e-mail: afritz@biology.emory.edu ) 10 4 2002 © 2002. 2002 Zebrafish dlx3 dlx7 Otic placode Olfactory placode The vertebrate ear and nose...
Journal Articles
Journal: Development
Development (1988) 103 (Supplement): 185–193.
Published: 1 September 1988
...Thomas R. Van De Water Statoacoustic ganglion neurones (SAG) are produced by the same group of cells (otic placode) that produce all of the receptor cells that populate the sensory areas of the inner ear. The observation that ingrowth of SAG neurites to presumptive sensory areas of the inner ear...