... interactions that govern rapid developmental processes. Fig. 5 shows the pattern of expression of the osterix ( Osx ; Sp7 – Mouse Genome Informatics) gene ( Rodda, 2006 ) in the heads of typically developing Osx -GFP mice at various harvesting times as demonstration of the ability of the staging system...

... expressing GFP under the control of the Prx1 promoter. Double-positive cells for Prx1-GFP and stem cell antigen-1 (Sca1) (Prx1 + Sca1 + cells) in the calvaria expressed Runx2 at lower levels and were more homogeneous and primitive than Prx1 + Sca1 − cells. Osterix (Osx) is another transcriptional determinant...

.... , Zhou , X. , Kunkel , G. , Zhang , Z. , Deng , J. M. , Behringer , R. R. and de Crombrugghe , B. ( 2002 ). The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation . Cell 108 , 17 - 29 . 10.1016/S0092-8674...

... that scleraxis (Scx) and osterix (Osx) antagonistically regulate tensile force-responsive PDL fibrogenesis and osteogenesis. In the developing PDL, Scx was induced during tooth eruption and co-expressed with Osx. Scx was highly expressed in elongated fibroblastic cells aligned along collagen fibers, whereas Osx...

... of Developmental and Cell Biology, UCI, Irvine,CA 92697, USA 1 10 2008 © 2008. 2008 Cyp26b1 Retinoic acid Bmp2 Cartilage Bone Chondrocyte Osteoblast Osteopontin Osterix Craniofacial development Vertebra Zebrafish Skeletal development is highly conserved in vertebrates...

... that must be exquisitely balanced to ensure proper skull vault formation. * Corresponding author (e-mail: loomic01@med.nyu.edu ) 19 10 2005 © 2006. 2006 Calvarial bone En1 Osterix Osteoblasts Osteoclasts The mammalian skull vault (roof) comprises...