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Keywords: Organogenesis
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Journal Articles
Journal: Development
Development (2022) 149 (1): dev199900.
Published: 4 January 2022
... Epidermal growth factor Organogenesis Microfluidics Kanton Zürich Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung http://dx.doi.org/10.13039/501100001711 310030_184792 Krebsliga Schweiz http://dx.doi.org/10.13039/501100004361 4377-02-2018...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (22): dev192500.
Published: 23 November 2020
... embryonic development, and highlight the presence of largely autonomous but interconnected developmental modules that orchestrate organogenesis. * Present address: Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany. ‡ Author...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (6): dev186213.
Published: 30 March 2020
... islet development exhibit striking similarities to human islet ontogeny, providing a novel resource for advancing human islet replacement strategies. Pancreas Metabolism Organogenesis β-Cell α-Cell δ-cell Diabetes mellitus Pig Progress from studies of pancreas biology in humans...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (3): dev183624.
Published: 7 February 2020
... guidance during myogenesis, along with a unique experimental framework to further investigate the mechanisms involved. FGF signaling Myogenesis Organogenesis Myotube guidance Rho GTPase Actin cytoskeleton Heartless Drosophila embryogenesis In mature skeletal muscle, myofibers...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (12): dev178673.
Published: 12 June 2019
.... Kidney development Single cell RNA-seq Organogenesis Nephron progenitor Ureteric epithelium Mammalian kidney development has been studied using the mouse for over 70 years. The developing mammalian kidney consists of three main cell lineages, all of which derive from multipotent progenitors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (18): dev162115.
Published: 21 September 2018
...Eric D. Bankaitis; Matthew E. Bechard; Guoqiang Gu; Mark A. Magnuson; Christopher V. E. Wright ABSTRACT During mouse pancreas organogenesis, endocrine cells are born from progenitors residing in an epithelial plexus niche. After a period in a lineage-primed Neurog3 LO state, progenitors become...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2018) 145 (14): dev164848.
Published: 23 July 2018
... haustorium organogenesis in parasitic plants. * Author for correspondence ( ken.shirasu@riken.jp ) Competing interests The authors declare no competing or financial interests. 7 3 2018 18 6 2018 © 2018. Published by The Company of Biologists Ltd 2018 This is an Open Access...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (24): 4481–4495.
Published: 15 December 2017
...-licence-1-1/ Summary: This Review describes the actions of cell fusogens during the three stages of developmental cell-cell fusion: the dehydration of plasma membranes, hemifusion, and fusion pore opening and expansion. Fertilization Fusogen Gamete fusion Mating Organogenesis Cell-cell...
Journal Articles
Journal: Development
Development (2017) 144 (17): 3007–3011.
Published: 1 September 2017
... at this 2017 EMBO Conference. Stem cell Regenerative medicine Epigenetics Metabolism Regulation Organogenesis One of the ultimate goals of stem cell biologists is to learn more about the development, homeostasis and regeneration of organisms, and to apply this knowledge to understand disease...
Journal Articles
Journal: Development
Development (2017) 144 (16): 2873–2888.
Published: 15 August 2017
... to underlie pancreas development, from induction and lineage formation to morphogenesis and organogenesis. Elucidating such principles will help to identify novel candidate disease genes and unravel the pathogenesis of pancreas-related diseases, such as diabetes, pancreatitis and cancer...
Journal Articles
In collection:
Human development
Journal: Development
Development (2017) 144 (13): 2338–2351.
Published: 1 July 2017
... cells provides a detailed spatiotemporal analysis of marker expression and tissue formation during corneal development. Human induced pluripotent stem cells Ocular differentiation Organogenesis Corneal organoids At 10 weeks, the MC-3 that developed in situ was strikingly similar...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (9): 1584–1587.
Published: 1 May 2017
...J. Gray Camp; Barbara Treutlein Innovative methods designed to recapitulate human organogenesis from pluripotent stem cells provide a means to explore human developmental biology. New technologies to sequence and analyze single-cell transcriptomes can deconstruct these ‘organoids’ into constituent...
Journal Articles
Journal: Development
Development (2017) 144 (6): 946–951.
Published: 15 March 2017
... the measurements performed in organoids to understand the role of chemical diffusion, contact signaling, differential cell adhesion and mechanical controls. Here, we discuss what it means to take a biophysical approach to understanding organogenesis in vitro and how we might expect such approaches to develop...
Journal Articles
Journal: Development
Development (2017) 144 (4): 687–697.
Published: 15 February 2017
... provided that the original work is properly attributed. Summary: Two parallel sensory lines in medaka share a common origin and are composed of identical organs that are, nevertheless, generated through different morphogenetic programmes. Organogenesis Lateral line Cxcr4b Cxcr7 Eya1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (3): 464–478.
Published: 1 February 2017
... that intestinal smooth muscle originates from the lateral plate mesoderm. Migration and differentiation of these cells involves TGFβ signaling. Zebrafish Organogenesis Lateral plate mesoderm Smooth muscle cells Smooth muscle cells (SMCs) constitute a vital proportion of various organs, including...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (22): 4149–4160.
Published: 15 November 2016
... direct evidence of an anteroposterior nuclear β-CATENIN-1 gradient in adult planarians and uncover novel, context-dependent roles for β-catenin-1 during anterior regeneration and organogenesis. The hypothesis that a dynamic morphogenetic gradient of axial potential underlies the re-establishment...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (9): 1491–1501.
Published: 1 May 2016
... birth owing to organogenesis defects as in ciliopathies. Shh signaling is impaired in null embryos and primary cilia are reduced in multiple tissues. We show that CP110 is required for anchoring of basal bodies to the membrane during cilia formation. CP110 loss resulted in an abnormal distribution...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (4): 554–565.
Published: 15 February 2016
... recent findings regarding stomach stem cells and organoid cultures, and their roles in investigating stomach diseases. Epithelial-mesenchymal interactions Organogenesis Transcriptional control of development A stomach is a muscular and characteristically curved portion of the proximal...
Journal Articles
Journal: Development
Development (2016) 143 (2): 306–317.
Published: 15 January 2016
... transcription factors Signaling pathway receptors Fibroblast growth factor receptor Wnt signaling pathway receptors Gene regulation Cardiac progenitor specification Cardiac mesoderm specification Heart development Cardiogenesis Organogenesis The rhythmically contracting heart of Drosophila...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (11): 1912–1917.
Published: 1 June 2015
... lung organoids. Summary: A recent Keystone meeting brought together researchers interested in diverse aspects of endoderm development and highlighted recent major advances in the field. Endoderm Keystone Development Disease Organogenesis Stem cells Progenitors The first...