... and Fishell, 2010 ; Ulloa and Marti, 2010 ). Organ growth CNS Interkinetic nuclear migration Asymmetric cell division Centrosome Growth factors Primary microcephaly Summary: This Review discusses the multiple roles played by centrosomes during embryonic growth of the vertebrate central...

...://www.biologists.com/user-licence-1-1/ Summary: Temporal and spatial patterns of Hippo signaling seen during Drosophila wing development are related to changes in mechanical stress, resulting from alterations in cell density and cytoskeletal tension. Hippo Stress Biomechanics Yorkie Organ growth...

... Progenitor proliferation Organ growth Correct organ development relies on the balance between cell proliferation, differentiation and death. The developing Drosophila eye is a powerful model with which to study these mechanisms and their integration because the progression through different...

... FGF Gremlin 1 Hox genes Shh Limb development Organ growth Mouse One of the most intriguing issues in developmental biology is how organ growth and patterning are coordinated during embryogenesis. For example, in vertebrates, the formation of the main body plan is achieved...

... in restricting the activation of the wg pathway and, by doing so, controls hinge growth. Here we describe a novel negative-feedback mechanism in the wg pathway that is required to restrain the expression of wg itself, and which is essential to control organ growth. * Author for correspondence...

... and mesenchymal cells to stimulate organ growth with few alterations in differentiation and patterning. References Bellusci, S., Furuta, Y., Rush, M. G., Henderson, R., Winnier,G. and Hogan, B. L. ( 1997a ). Involvement of Sonic hedgehog(Shh) in mouse embryonic lung growth and morphogenesis. Development...

... of other target genes such as Dll ). The dramatic expansion of the Drosophila wing primordium following the D-V compartmental segregation provides a valuable paradigm of organ growth. Growth in this context is manifest as a rapid ∼200-fold expansion of the population of cells expressing the wing...

.... * Author for correspondence (e-mail: gs20@columbia.edu ) 12 6 2007 © 2007. 2007 Drosophila wing Morphogen Organ growth Selector gene Vestigial Wingless signaling All animals are composed of distinct body parts and organs, many of which are specified by particular...