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Keywords: Optic nerveClose
Bruce A. Rheaume, Jian Xing, Agnieszka Lukomska, William C. Theune, Ashiti Damania, Greg Sjogren, Ephraim F. Trakhtenberg
Development (2023) 150 (8): dev201644.
Published: 24 April 2023
...-regenerating RGCs for single-cell RNA-sequencing analysis reveals that adult neuronal subtypes that retain features of the embryonic cell state dedifferentiate in response to a treatment. Axon growth Optic nerve Retinal ganglion cell scRNA-seq Mouse School of Medicine, University...
Includes: Supplementary data
Development (2013) 140 (13): 2711–2723.
Published: 1 July 2013
... of the optic nerve. Genetic evidence further supports that the formation of an Frs2α-Shp2 complex and its recruitment to FGF receptors are crucial for downstream ERK signaling in this process, whereas constitutively active Ras signaling can rescue ocular coloboma in the FGF signaling mutants. Our results thus...
Includes: Supplementary data
Yoshihiko Sugimoto, Masahiko Taniguchi, Takeshi Yagi, Yoshio Akagi, Yoshiaki Nojyo, Nobuaki Tamamaki
Development (2001) 128 (17): 3321–3330.
Published: 1 September 2001
... in the neuroepithelium. We investigated the guidance mechanisms of glial precursor (GP) cell migration in the optic nerve. GP cell migration in newborn rat optic nerve was monitored by the UV-thymine-dimer (TD) method. A double labeling study using NG2 and TD revealed that many of these in vivo migrating cells were NG2...
Development (1997) 124 (5): 937–948.
Published: 1 March 1997
...Dietmar Schmucker; Herbert Jäckle; Ulrike Gaul ABSTRACT The Drosophila larval optic nerve, called Bolwig’s nerve (BN), projects into the central brain along a simple invariant path. The growth of the BN proceeds in three phases, during which the nerve changes direction at two intermediate targets...
Development (1993) 118 (2): 539–552.
Published: 1 June 1993
...Hardeep S. Mudhar; Richard A. Pollock,; Chiayeng Wang; Charles D. Stiles; William D. Richardson ABSTRACT We have used in situ hybridization to visualize cells in the developing rat retina and optic nerve that express mRNAs encoding the A and B chains of platelet-derived growth factor (PDGF...
Development (1990) 109 (3): 691–698.
Published: 1 July 1990
...Guus Wolswijk; Peter N. Riddle; Mark Noble ABSTRACT We have studied the developmental appearance of the O-2A adult progenitor cell, a specific type of oligodendro cyte-type-2 astrocyte (O-2A) progenitor cell that we have identified previously in cultures prepared from the optic nerves of adult rats...
Development (1989) 105 (2): 387–400.
Published: 1 February 1989
...Guus Wolswijk; Mark Noble ABSTRACT We have found that glial progenitor cells isolated from the optic nerves of adult rats are fundamentally different from their counterparts in perinatal animals. In our studies on bipotential oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells, we have seen...
Development (1987) 99 (3): 393–410.
Published: 1 March 1987
...J. S. H. Taylor ABSTRACT This study concerns the retinotopic organization of the ganglion cell fibres in the visual system of the frog Xenopus laevis . HRP was used to trace the pathways taken by fibres from discrete retinal positions as they pass from the retina, along the optic nerve...
Development (1985) 89 (1): 383–401.
Published: 1 October 1985
... & Stelzner, 1981 a,b,c ). The visual system in amphibians and fishes has, however, provided a generally accepted model for the study of regenerating optic nerve fibres. It now appears that this also may be questionable. At one month after metamorphosis, when many of these experiments have been performed...