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Keywords: Optic chiasm
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2017) 144 (13): 2504–2516.
Published: 1 July 2017
... now provided in vivo evidence for a cell-autonomous requirement of NRP1 signalling in RGCs to regulate midline crossing of their axons at the optic chiasm as well as axon fasciculation, particularly in the ipsilateral optic tract. The role of NRP1 in midline crossing was consistent with prior...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (6): 1035–1044.
Published: 15 March 2006
...Jill A. Sakai; Mary C. Halloran The optic chiasm is an important choice point at which retinal ganglion cell (RGC) axons either cross the midline to innervate the contralateral brain or turn back to innervate the ipsilateral brain. Guidance cues that regulate this decision, particularly those...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (15): 3371–3379.
Published: 1 August 2005
..., they cross to the contralateral side of the brain at the optic chiasm. Second, they turn caudally in the mid-diencephalon. Finally,they must recognize the optic tectum as their target. The matrix metalloproteinase (MMP) and a disintegrin and metalloproteinase (ADAM)families are zinc (Zn)-dependent...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3773–3784.
Published: 1 August 2004
...Thomas Pratt; Natasha M. M.-L. Tian; T. Ian Simpson; John O. Mason; David J. Price During normal development, retinal ganglion cells (RGCs) project axons along the optic nerve to the optic chiasm on the ventral surface of the hypothalamus. In rodents, most RGC growth cones then cross the ventral...
Journal Articles
Journal: Development
Development (2000) 127 (5): 969–980.
Published: 1 March 2000
... to progress normally from the optic chiasm into the optic tracts. The underlying cause is unknown but, in principle, can result from either the disruption of guidance mechanisms that mediate axon exit from the midline chiasm region or defects in growth cone signaling required for entry into the lateral...
Journal Articles
Journal Articles
Journal: Development
Development (1993) 117 (2): 725–735.
Published: 1 February 1993
... to all other retinal axons they seem to be deflected from the midline of the optic chiasm and thereby led into the ipsilateral optic tract. In order to analyse the interactions between growing fibres and chiasm midline, we have developed the following in vitro model. Axons of the embryonic rat retina...
Journal Articles
Journal: Development
Development (1990) 108 (3): 515–523.
Published: 1 March 1990
... and Jeffery, 1989 ). The distribution of uncrossed axons thus indicates that positional cues are not sufficient to account for the choice made by axons when they reach the optic chiasm. 05 01 1990 © 1990 by Company of Biologists 1990 optic chiasm axonal pathway optic axons Dil...
Journal Articles
Journal: Development
Development (1987) 101 (4): 857–867.
Published: 1 December 1987
... by Company of Biologists 1987 albino retinofugal mosaicism optic chiasm mouse. Albino mammals have an abnormally reduced uncrossed retinofugal pathway ( Lund, 1965 ; Guillery & Kaas, 1971 ; Creel, Hendrickson & Leventhal, 1982 ). The way in which the albino gene produces...