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Keywords: Nrf2
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Journal Articles
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Neural development
Journal: Development
Development (2022) 149 (17): dev200342.
Published: 30 August 2022
... , which encodes Nrf2, is a pivotal executor of Perk signaling that regulates neuronal phenotypes in aars1 cq71/cq71 mutants. Interference of nfe2l2b in nfe2l2b Δ1/Δ1 mutants did not affect global larval development. However, aars1 cq71/cq71 ;nfe2l2b Δ1/Δ1 mutant embryos exhibited increased neuronal cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (3): dev171520.
Published: 1 February 2019
... is undiscernible in germ-free larvae, but forms following monocolonization with L. plantarum . L. plantarum is a strong activator of the ROS-sensitive CncC/Nrf2 signaling pathway within enterocytes. Enterocyte-specific activation of CncC stimulated the proliferation of AMPs, which demonstrates that pro...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (24): 4588–4603.
Published: 15 December 2017
... of transcription factor Nrf2. Knockout of Arpc4 in cultured keratinocytes was sufficient to induce nuclear accumulation of Nrf2, upregulation of Nrf2 target genes and decreased filamentous actin levels. Furthermore, pharmacological inhibition of the Arp2/3 complex unmasked the role of branched actin filaments...
Includes: Supplementary data