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Keywords: Node
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Journal Articles
Journal Articles
Journal: Development
Development (2011) 138 (18): 3915–3920.
Published: 15 September 2011
...Yoshihiro Komatsu; Vesa Kaartinen; Yuji Mishina Cilia at the node generate a leftward fluid flow that breaks left-right symmetry. However, the molecular mechanisms that regulate ciliogenesis at the node are largely unknown. Here, we show that the epiblast-specific deletion of the gene encoding...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (23): 3917–3925.
Published: 1 December 2009
...Shinya Oki; Keiko Kitajima; Sara Marques; José António Belo; Takahiko Yokoyama; Hiroshi Hamada; Chikara Meno The node at the anterior tip of the primitive streak serves as an initial generator of the left-right (L-R) axis in mammalian embryos. We now show that a small disturbance in molecular...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2007) 134 (15): 2829–2840.
Published: 1 August 2007
..., the chordoneural hinge, but the localisation of such progenitors at earlier stages is so far untested. By studying gene expression, we have shown that a specific topological arrangement of domains persists from the streak to the tail bud, and includes an area (the node-streak border) in which ectoderm...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (2): 297–306.
Published: 15 January 2006
... regulated by the coordination of five phylogenetically conserved enhancers having discrete regional coverage, among which the 420-bp long enhancer N-1, active in the node-proximal region, is probably involved directly in the genesis of the posterior neural plate. We investigated the signaling systems...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (21): 4719–4729.
Published: 1 November 2005
...Atsushi Sawada; Yuriko Nishizaki; Hiroko Sato; Yukari Yada; Rika Nakayama; Shinji Yamamoto; Noriyuki Nishioka; Hisato Kondoh; Hiroshi Sasaki The cell population and the activity of the organizer change during the course of development. We addressed the mechanism of mouse node development via...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (2): 263–274.
Published: 15 January 2004
... requirement for a repressor function of Lef/Tcf proteins during early mouse development. Tcf3 -/- embryos proceed through gastrulation to form mesoderm, but they develop expanded and often duplicated axial mesoderm structures, including nodes and notochords. These duplications are preceded by ectopic...
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (9): 1725–1734.
Published: 1 May 2003
... that the fusion protein is functional. In transgenic embryos, Inv::GFP protein was detected in the node monocilia. The fusion protein was also present in other 9+0 monocilia,including those of kidney epithelial cells and the pituitary gland, but it was not localized to 9+2 cilia. The N-terminal region of Inv...
Includes: Multimedia, Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (15): 3597–3608.
Published: 1 August 2002
... mesoderm, the heart and the gut during embryogenesis. ‡Author for correspondence (e-mail: robb@wehi.edu.au ) 30 4 2002 © 2002. 2002 Mix Bix Homeobox Gastrulation Mesendoderm Notochord Node Endoderm Mouse In Xenopus, members of the Mix/Bix family of Paired -like...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3623–3634.
Published: 15 September 2001
... , and the ability of these cells to induce a second neural axis in the host embryo. This cell population can therefore be regarded as the mid-gastrula organizer and, together with the early-gastrula organizer and the node, constitute the organizer of the mouse embryo at successive stages of development. The profile...
Journal Articles
Journal: Development
Development (2001) 128 (10): 1831–1843.
Published: 15 May 2001
... ) * Present address: Department of Periodontology and Endodontology, Osaka University Faculty of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan 23 02 2001 19 04 2001 © 2001 by Company of Biologists 2001 nodal Anteroposterior axis Left-right asymmetry Node Lateral plate...
Journal Articles
Journal: Development
Development (1997) 124 (2): 429–442.
Published: 15 January 1997
... mesoderm. In the first domain of expression, Cryptic expression is progressively localized to the anterior primitive streak, the head process, and the node and notochordal plate. In the second domain, Cryptic expression is initially concentrated in the lateral region of the egg cylinder, and is later found...
Journal Articles
Journal: Development
Development (1996) 122 (1): 243–252.
Published: 1 January 1996
... besides proliferation are also affected in the mutants. A very similar extraembryonicembryonic constriction was also observed in HNF-3 β mutants ( Ang and Rossant, 1994 ; Weinstein et al., 1994 ) and to a lesser extent in Lim-1 mutants ( Shawlot and Behringer, 1995 ), both of which also affect node...
Journal Articles
Journal Articles
Journal: Development
Development (1995) 121 (2): 273–285.
Published: 1 February 1995
... mesoderm is detected in eed mutant embryos, and there is no subsequent organization of mesoderm into node, notochord, or somites. The phenotype is consistent with a defect in the distal primitive streak. Here we report additional phenotypic analyses that include mRNA in situ hybridization of genes whose...
Journal Articles
Journal: Development
Development (1994) 120 (3): 613–620.
Published: 1 March 1994
..., until now there has been no direct evidence that the mouse node organizes pattern during gastrulation, nor that the exceptionally small mouse embryonic egg cylinder can be induced to form a second axis. Grafts of transgenically marked mid-gastrulation mouse node, or node labelled with DiI...