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Keywords: Ngn2
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Journal Articles
Journal: Development
Development (2012) 139 (13): 2308–2320.
Published: 1 July 2012
... Ascl1 ( Mash1 ), Neurog1 ( Ngn1 ) and Neurog2 ( Ngn2 ), and represent suitable candidate regulators of PC development. They are expressed in partially overlapping domains in the Ptf1a + cbVZ, possibly contributing to its regionalization. Ascl1 + progenitors contribute to PCs and GABAergic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (10): 1718–1723.
Published: 15 May 2012
...Christopher Hindley; Fahad Ali; Gary McDowell; Kevin Cheng; Alison Jones; Francois Guillemot; Anna Philpott Neurogenin 2 (Ngn2) controls neuronal differentiation cell-autonomously by transcriptional activation of targets such as NeuroD , while simultaneously controlling progenitor maintenance non...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (19): 4267–4277.
Published: 1 October 2011
... that occurs as development progresses. However, the mechanistic basis of this regulation is unknown. The proneural transcription factor Neurogenin 2 (Ngn2) acts as a master regulator of neuronal differentiation. Here, we demonstrate that Ngn2 is phosphorylated on multiple serine-proline sites in response...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (13): 2823–2832.
Published: 1 July 2011
...Joanna S. T. Asprer; Bora Lee; Chia-Shan Wu; Tegy Vadakkan; Mary E. Dickinson; Hui-Chen Lu; Soo-Kyung Lee The proneural protein neurogenin 2 (NGN2) is a key transcription factor in regulating both neurogenesis and neuronal radial migration in the embryonic cerebral cortex. However, the co-factors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (20): 3459–3470.
Published: 15 October 2008
... pathway that controls the differentiation of mesDA neurons shows that, in the absence of Otx2, the expression of Lmx1a and Msx1 , and the proneural genes Ngn2 and Mash1 is not activated in Sox2 + mesDA progenitors, which largely fail to differentiate into Nurr1 + mesDA precursors. Furthermore...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (9): 1949–1959.
Published: 1 May 2003
...@utsouthwestern.edu ) 30 1 2003 © 2003. 2003 bHLH transcription factors Transcriptional regulation Transcription repressors Chick electroporation Dorsal spinal cord development Neuronal differentiation Math1/Cath1 Mash1/Cash1 Ngn1 Ngn2 The differentiation of a proliferating neural...