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Keywords: Neurons
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (8): dev200425.
Published: 3 May 2022
... of the brain. Apart from being highly specialized brain phagocytes, microglia modulate the development and functions of neurons and glial cells through both direct and indirect interactions. Thus, recognizing the elements that influence the homeostasis and heterogeneity of microglia in normal brain development...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (14): dev176735.
Published: 22 July 2019
... from proliferating progenitors to differentiated neurons. Functional experiments demonstrated the pivotal role of Yap/Taz-TEAD signaling in maintaining progenitor features in the hindbrain boundary cell population. © 2019. Published by The Company of Biologists Ltd 2019 http://www.biologists.com...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (10): 1983–1986.
Published: 15 May 2014
...Simon M. G. Braun; Sebastian Jessberger New neurons are generated throughout life in distinct regions of the mammalian brain. This process, called adult neurogenesis, has been implicated in physiological brain function, and failing or altered neurogenesis has been associated with a number...
Journal Articles
Journal: Development
Development (2013) 140 (2): 323–332.
Published: 15 January 2013
... has been made by studying the zebrafish parapineal organ, a group of neurons on the left side of the epithalamus. Parapineal cells arise from the medially located pineal complex anlage and migrate to the left side of the brain. We have found that Fgf8a regulates a fate decision among anterior pineal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (18): 3392–3401.
Published: 15 September 2012
... Receptor (EcR-B1) expression in MB neurons. This is phenocopied in CORL-RNAi and Smad2-RNAi clones in wild-type larvae. Furthermore, constitutively active Baboon (type I receptor upstream of Smad2) cannot stimulate EcR-B1 MB expression in Df(4)dCORL larvae, which demonstrates a formal requirement for CORL...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (16): 2878–2890.
Published: 15 August 2012
...Matthew V. Covey; Jeffrey W. Streb; Roman Spektor; Nurit Ballas REST is a master repressor of neuronal genes; however, whether it has any role during nervous system development remains largely unknown. Here, we analyzed systematically the role of REST in embryonic stem cells and multipotent neural...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (17): 2885–2894.
Published: 1 September 2010
... pathway in clones of cells to study their effects on nerve pathfinding within the peripheral nervous system. We find that high levels of Engrailed make the epidermal cells inhospitable to bristle neurons; sensory axons that are too near these cells are either deflected or fail to extend properly or at all...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (15): 2583–2592.
Published: 1 August 2008
... in neuronal function in postmitotic,differentiated neurons. Here, we demonstrate a novel role for the canonical Notch signalling pathway in postmitotic neurons during a specialised`diapause-like' post-embryonic developmental stage in C. elegans called dauer. Our data suggest that cell signalling downstream...
Journal Articles
Journal: Development
Development (2006) 133 (10): 1911–1921.
Published: 15 May 2006
...Robert P. Johnson; Seong Hoon Kang; James M. Kramer The C. elegans dystroglycan (DG) homolog DGN-1 is expressed in epithelia and neurons, and localizes to basement membrane (BM) surfaces. Unlike vertebrate DG, DGN-1 is not expressed in muscle or required for muscle function. dgn-1 null mutants...
Journal Articles
Journal: Development
Development (2005) 132 (8): 1951–1959.
Published: 15 April 2005
... signalling. Dbx-expressing precursors also generate astrocytes and interneurons, but do not contribute to the ependymal layer of the postnatal spinal cord. * Author for correspondence (e-mail: w.richardson@ucl.ac.uk ) 10 2 2005 ©2005. 2005 Dbx Cre Spinal cord Radial glia Neurons...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3717–3726.
Published: 1 August 2004
...-mediated gene transfer in cortical organotypic slice cultures established from early postnatal mice to study the effects of HGF on the development of dendritic arbors of pyramidal neurons. Compared with untreated control cultures, exogenous HGF promoted a highly significant increase in dendritic growth...
Journal Articles
Journal: Development
Development (2003) 130 (19): 4553–4566.
Published: 1 October 2003
... be stimulated by expression of activated EGL-30 in neurons, or by an EGL-30-dependent change in behavior that occurs in a liquid environment. Our results indicate that excitable cells and animal behavior can provide modulatory inputs into the effects of growth factor signaling on cell fates,and suggest...
Journal Articles
Journal: Development
Development (2003) 130 (10): 2187–2198.
Published: 15 May 2003
.... These analyses demonstrate that glial cell line-derived neurotrophic factor (GDNF) and neurturin are important for different aspects of ENS development. Neurturin is essential for maintaining the size of mature enteric neurons and the extent of neuronal projections, but does not influence enteric neuron number...
Journal Articles
Journal: Development
Development (2002) 129 (12): 2785–2796.
Published: 15 June 2002
...Alan J. Burns; Jean-Marie M. Delalande; Nicole M. Le Douarin The enteric nervous system (ENS) is derived from vagal and sacral neural crest cells (NCC). Within the embryonic avian gut, vagal NCC migrate in a rostrocaudal direction to form the majority of neurons and glia along the entire length...