... characterised progenitor diversity and disentangled the gene modules underlying temporal versus spatial regulations of neuronal specification. Finally, we reconstructed the developmental trajectories followed by ventral and dorsal pallial neurons to identify lineage-specific gene waves. Our data suggest a model...

.... Summary: Spatial patterning of transcription factor activity among proprioceptive sensory neurons innervating different targets is required for their further specification and for sensorimotor connectivity. Sensory system Sensorimotor circuit Dorsal root ganglia Neuronal specification...

.... ( 2008 ). A dlx2- and pax6-dependent transcriptional code for periglomerular neuron specification in the adult olfactory bulb . J. Neurosci. 28 , 6439 – 6452 . Brill M. S. , Ninkovic J. , Winpenny E. , Hodge R. D. , Ozen I. , Yang R. , Lepier A. , Gascón S...

...-heidelberg.mpg.de ) Competing interests statement The authors declare no competing financial interests. 11 2 2013 © 2013. Published by The Company of Biologists Ltd 2013 Hypothalamus Neuronal specification Zebrafish Mammillary area Fezf2 Vasoactive intestinal peptide...

... between the mechanisms controlling the laminar position and identity of cortical neurons. * Authors for correspondence ( anton@med.unc.edu ; nenad.sestan@yale.edu ) Competing interests statement The authors declare no competing financial interests. © 2012. Neuronal specification...

... ). Cyclin D2 Neuronal specification Neurogenesis Cerebellum Mouse © 2011. 13 6 2011 Competing interests statement The authors declare no competing financial interests. * Author for correspondence ( ferdinando.rossi@unito.it ) The different types...

...-Retzius cells Fgf8 signalling Forebrain development Neuronal specification Mouse The cerebral cortex contains different subclasses of excitatory projection neurons derived from the dorsal telencephalon or pallium, as well as inhibitory interneurons originating from the ventral telencephalon...

... expression of dbx relative to that of eve and hb9 in sibling neurons is crucial for proper neuronal specification, as misexpression of dbx in motoneurons dramatically hinders motor axon outgrowth. 24 7 2009 © 2009. © 2009. 2009 dbx Neuronal specification Drosophila eve hb9 CNS...

...-mail: gil.levkowitz@weizmann.ac.il ) 26 8 2008 © 2008. 2008 Cell number Neuronal specification Oxytocin Dopamine Cell lineage Neural patterning cues, such as Wnt, provide progenitor cells with distinct positional identity and induce proneural proteins, which in turn initiate...

... Neuronal specification Proliferation Mouse © 2006. 2006 12 5 2006 * Author for correspondence (e-mail: kmillen@genetics.bsd.uchicago.edu ) ...

... to rescue, at least partially, cell cycle exit and the number of dorsal neurons in Mash1 mutant mice, but not the deficit in neuronal specification ( Parras et al.,2002 ; Pattyn et al.,2004 ). This should cause an increase in dILB neurons in Mash1 Ngn2 /Mash1 Ngn2 compared with Mash1 –/– mice...

... the region where dI2-dI5 are formed ( Fig. 1A ). As a first step in examining the roles of Mash1 and Ngn2 in dorsal neuron specification,we examined their colocalization in detail at E10.5 using previously characterized rabbit polyclonal antibodies against Mash1( Horton et al., 1999 ) and mouse monoclonal...

... pattern in mouse gastrulation and neurogenesis. Dev. Dyn. 208 , 92 -106. Jessell, T. M. ( 2000 ). Neuronal specification in the spinal cord:inductive signals and transcriptional codes. Nat. Rev. Genet. 1 , 20 -29. Jouve, C., Palmeirim, I., Henrique, D., Beckers, J., Gossler,A., Ish-Horowicz...

... studies of neuronal specification in the spinal cord have taken advantage of the topographic organization of motoneurons into specific muscle pools ( Hollyday, 1980a ; Hollyday, 1980b ; Landmesser, 1978 ) to delineate their transcriptional program. Both LIM homeodomain transcription factors and members...

... cells were detected with anti-BrdU antibody. The ratio of BrdU labelled cells is slightly increased in the Pax6 mutant (t-test; *P<0.001). Fig. 8. The proposed model of Pax6 function in neuronal specification. The model indicates that Pax6 functions in establishment of progenitor domains...

... with axons destined for the same nerve, suggesting that fasciculation may aid pathfinding. * Author for correspondence (e-mail: mhonig@utmen1.utmem.edu ) 17 02 1998 02 01 1997 © 1998 by Company of Biologists 1998 Pathfinding Neuronal specification Axonal guidance...