... is a specific marker for bipotent neuronal progenitors, expressed in cycling interstitial cells that give rise to apical neurons and gastric nematoblasts (i.e. sensory mechanoreceptor precursors). cnox-2 RNAi silencing leads to a dramatic downregulation of hyZic, prdl-a, gsc and cnASH , whereas hyCOUP-TF...

... described for other ventral specification genes, such as MNR2 / HB9 during motoneuron specification ( Tanabe et al.,1998 ) or Phox2b ( Dubreuil et al., 2000 ). Using both loss- and gain-of-function studies, we have established that Gata2 exerts negative control on the division of neuronal progenitors...