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Keywords: Neuregulin
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Journal Articles
Journal: Development
Development (2021) 148 (19): dev198937.
Published: 04 October 2021
... Hartstichting http://dx.doi.org/10.13039/501100002996 The Netherlands CardioVascular Research Initiative Prrx1 Neuregulin Zebrafish Heart regeneration Fibrosis Fibroblasts Highlighted Article: Epicardial-expressed Prrx1 ensures a balance between the fibrotic response...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (7): 1336–1345.
Published: 01 April 2015
... is regulated by an autocrine activation of the EGF receptor through the neuregulin homolog Vein. This resembles the molecular mechanism employed during cell-autonomous reactivation of glial differentiation after injury in mammals. We further demonstrate that Vein, produced by the wrapping glia, also regulates...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (21): 4110–4114.
Published: 01 November 2014
... neuregulin-like called vein ( vn ). Here, we used mutant combinations and gene replacement to determine the constraints of ligand specificity in development. Mutant analysis revealed extensive ligand redundancy in embryogenesis and wing development. Surprisingly, we found that the essential role of vn...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (21): 4639–4648.
Published: 01 November 2011
... that these glial cells properly associate with axons. ErbB receptors are required for Schwann cell migration, but the operative ligand and its mechanism of action have remained unknown. We demonstrate that zebrafish Neuregulin 1 (Nrg1) type III, which signals through ErbB receptors, controls Schwann cell migration...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (15): 2615–2625.
Published: 01 August 2008
... isolated three genes encoding neuregulins, ErbB3 ligands, and show that two neuregulins function together in zebrafish trunk neural crest cell migration and in DRG formation. Together,our results suggest that ErbB3 signaling is required for normal migration of trunk, but not cranial, neural crest cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (6): 1125–1132.
Published: 15 March 2006
... signals in the formation of this tissue. The differentiation of these specialized cells, unlike that of adjacent endocardial cushions and valves, is not dependent on blood flow or cardiac contraction. Finally, both neuregulin and notch1b are necessary for the development of atrioventricular conduction...
Includes: Multimedia, Supplementary data