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Keywords: Neural precursor
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Journal Articles
Journal: Development
Development (2008) 135 (19): 3291–3300.
Published: 1 October 2008
... mechanism through which IRS1 promotes SHH-stimulated CGNP proliferation may also identify novel targets for development of new treatments for medulloblastoma and other cancers. © 2008. 2008 Sonic hedgehog Cerebellum Neural precursor Insulin-like growth factor Insulin receptor substrate 1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (23): 5959–5969.
Published: 1 December 2004
... and subsequently specify oligodendrocyte development. Our studies show that spatial and temporal differences in Hh signaling within a common population of neural precursors can contribute to cell fate diversification. Fig. 6. Hh signaling is required for oligodendrocyte specification after dorsoventral...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (8): 1679–1689.
Published: 15 April 2004
... process of neural precursor cell (NPC) selection by basic helix-loop-helix (bHLH) proneural transcription factors in the peripheral nervous system (PNS) by atonal related proteins (ARPs) presents an excellent model in which to address this issue. Proneural ARPs belong to two highly related groups...
Journal Articles
Journal: Development
Development (2004) 131 (1): 217–228.
Published: 1 January 2004
... Medulloblastoma Myc Neural precursor Mouse Nmyc1 (N-myc) Although we were unable to establish culture conditions of sufficient duration to determine the effects of GSK3 inhibition on endogenous Nmyc1 accumulation, it has been reported that inhibition of GSK activity enhances CGNP proliferation (Cui et al...
Journal Articles
Journal: Development
Development (2003) 130 (1): 15–28.
Published: 1 January 2003
... Cerebellum Sonic hedgehog Proliferation Cyclopamine Medulloblastoma Nmyc Neural precursor TRRAP Mouse Signaling by the hedgehog family of secreted glycoproteins has been highly conserved through evolution ( Ingham and McMahon, 2001 ). Hedgehog activity is required for fundamental processes...