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Keywords: Neural patterning
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Journal Articles
Journal: Development
Development (2017) 144 (2): 258–264.
Published: 15 January 2017
... patterning of the vertebrate neural tube is conserved in a protochordate . Development   124 , 2335 - 2344 . Cornell , R. A. and Von Ohlen , T. V. ( 2000 ). Vnd/nkx, ind/gsh, and msh/msx: conserved regulators of dorsoventral neural patterning?   Curr. Opin. Neurobiol.   10 , 63 - 71...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (8): 1683–1693.
Published: 15 April 2014
.... , Papalopulu N. ( 1997 ). An essential role for retinoid signaling in anteroposterior neural patterning . Development 124 , 373 - 379 . Blythe S. A. , Reid C. D. , Kessler D. S. , Klein P. S. ( 2009 ). Chromatin immunoprecipitation in early Xenopus laevis embryos . Dev...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (2): 410–421.
Published: 15 January 2014
..., but expression of the anterior forebrain marker, xanf1 was increased ( Fig. 4D ). Pan-neural marker nrp1 expression is not significantly reduced in either PTK7 or LRP6 morphants, versus controls ( Fig. 4D , middle panel). Thus, neural patterning, but not neural induction is perturbed. Both morphant groups...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (5): 1034–1044.
Published: 1 March 2012
... The authors declare no competing financial interests. 3 1 2012 © 2012. Neural induction Neural plate Neural border Anterior neural ridge Secondary prosencephalon Forebrain Telencephalon Fate map Neural patterning Cell intercalation Vertical induction Chick...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (24): 5321–5331.
Published: 15 December 2011
... responsiveness Neural patterning Astrocytes are the most abundant cell type in the adult central nervous system (CNS). Despite their various roles in CNS function and homeostasis (for reviews, see Barres, 2008 ; Faissner et al., 2010 ; Haydon, 2001 ) their ontogenetic development remains poorly...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (22): 4921–4930.
Published: 15 November 2011
.... The neural patterning phenotype of PKA-null embryos is as strong as that in Ptch1 -null embryos. Although PKA has many different cellular functions ( Willis et al., 2011 ), the strikingly similar morphologies of PKA- and Ptch1 -null embryos suggests that the primary function of PKA in the early embryo...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (17): 3613–3623.
Published: 1 September 2011
..., Box 1 ). Below, we highlight the mechanisms of neural patterning that are shared among deuterostomes. The two themes of this model are that the embryo starts with two regulatory layers of broad overlapping neurogenic potential (the ANE and the CBE), each of which is sequentially downregulated...
Journal Articles
Journal: Development
Development (2010) 137 (9): 1531–1541.
Published: 1 May 2010
... interests. 17 2 2010 © 2010. 2010 Meis3 Wnt3a Neural patterning Dorsal-lateral marginal zone (DLMZ) Paraxial mesoderm Xenopus Secreted signals act via transcription factors to regulate the anteroposterior (AP) pattern in vertebrate nervous system development. Yet, little...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (3): 437–445.
Published: 1 February 2010
... Neural patterning Neurogenesis Notch pathway The establishment of the central nervous system (CNS) depends on the generation of functionally distinct neurons produced in appropriate numbers and at correct positions. In the developing spinal cord, distinct classes of neurons are produced...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (23): 4055–4063.
Published: 1 December 2009
.... 2009 Human embryonic stem cells Neural patterning Neural differentiation Sonic hedgehog Wnt signaling The development of diverse neuronal subtypes in the telencephalon begins with the specification of regional progenitors through inductive signals that are secreted from the patterning...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (14): 2457–2465.
Published: 15 July 2009
.... 2009 Forebrain FGF receptors Neural plate Neural patterning Mouse How a morphologically uniform sheet of cells becomes patterned into molecularly, functionally and structurally distinct areas remains one of the principal puzzles facing developmental biologists. In particular...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (19): 3449–3460.
Published: 1 October 2007
... cells derived from different rhombomeres( Fraser et al., 1990 ). The hRPe, as a result of these AP variations, might have the capacity to influence neural patterning along the AP as well as the DV axis. Roof plate epithelium (RPe), via the secretion of patterning signals and growth factors, induces...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (19): 3527–3537.
Published: 1 October 2007
... Neural patterning Nodal Delta Notch FGF MEK ERK The central nervous system (CNS) of the Ciona intestinalis larva is remarkably similar in overall organisation to, but much simpler than, its vertebrate counterpart. It consists of an anterior sensory vesicle, followed by a narrow neck...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (10): 1977–1989.
Published: 15 May 2007
... Chromatin immunoprecipitation Gli Neural patterning Sonic hedgehog Mouse The Hedgehog (Hh) signaling pathway represents one of approximately six core signaling pathways that dictate development in most bilateria( Davidson and Erwin, 2006 ; Hooper and Scott, 2005 ). Hh ligands regulate diverse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (7): 1335–1345.
Published: 1 April 2006
... the establishment of stereotypic patterns of axonal projection and neuronal migration (reviewed by Wilson and Rubenstein, 2000 ). Neural patterning Neuronal migration Telencephalon Pax6 Ephrin A5 © 2006. 2006 18 1 2006 * Author for correspondence (e-mail: osumi...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (6): 1199–1210.
Published: 15 March 2005
... at the 32-cell stage. Ci-Nodal is thus an excellent candidate for the signal responsible for patterning of the A-line neural lineages. In order to investigate the role of Nodal during neural patterning, three methods were chosen to inhibit Nodal signalling. Firstly, we used a pharmacological...
Journal Articles
Journal: Development
Development (2003) 130 (21): 5155–5167.
Published: 1 November 2003
... revealed a genetic network regulating vertebrate eye field specification. Our results support a model of progressive tissue specification in which neural induction then Otx2 -driven neural patterning primes the anterior neural plate for eye field formation. Next, the EFTFs form a self-regulating feedback...
Journal Articles
Journal: Development
Development (2003) 130 (20): 4907–4917.
Published: 15 October 2003
...Tomomi Haremaki; Yasuko Tanaka; Ikuko Hongo; Masahiro Yuge; Harumasa Okamoto Early neural patterning along the anteroposterior (AP) axis appears to involve a number of signal transducing pathways, but the precise role of each of these pathways for AP patterning and how they are integrated...
Journal Articles
Journal: Development
Development (2003) 130 (20): 4989–4998.
Published: 15 October 2003
... in the axial mesoderm for anterior neural development. Consistent with these results, bon -mutant embryos show defects in axial mesoderm gene expression starting at mid-gastrulation stages. In addition, genetic analyses demonstrate a functional interaction during neural patterning between bon and two...
Journal Articles
Journal: Development
Development (2003) 130 (16): 3821–3829.
Published: 15 August 2003
... ; Trainor and Krumlauf,2001 ). Vhnf1 Fibroblast growth factor Fgf3 Fgf8 Zebrafish Hindbrain Valentino Krox20 Rhombomere Neural patterning Fgf signals are reused throughout development and yet the cellular response to the signal varies based on time and location. In the developing...