1-20 of 29
Keywords: Neural induction
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2018) 145 (5): dev159525.
Published: 9 March 2018
... of responsiveness to organizer signals. Axial organization Spemann Body plan Neural induction Organizer Vertebrate embryo In the context of an embryo, an ‘organizer’ refers to a group of cells that harbour the ability to instruct fates and morphogenesis in surrounding cells, steering...
Journal Articles
Journal: Development
Development (2017) 144 (1): 33–37.
Published: 1 January 2017
... of Biologists Ltd 2017 http://www.biologists.com/user-licence-1-1/ Summary: Epidermal fate is autonomously determined by a gene circuit beginning with Sox1/2/3 and Tfap2-r.b in ascidian embryos. TFAP2 Sox1/2/3 Epidermis Ectoderm Neural induction In animal embryos, the ectoderm...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (17): 2864–2875.
Published: 1 September 2015
... . 10.1016/j.stem.2010.01.003 Greber , B. , Coulon , P. , Zhang , M. , Moritz , S. , Frank , S. , Müller-Molina , A. J. , Araúzo-Bravo , M. J. , Han , D. W. , Pape , H.-C. and Schöler , H. R. ( 2011 ). FGF signalling inhibits neural induction in human...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (12): 2611–2618.
Published: 15 June 2013
... target of miR-96 family members via gain- and loss-of-function analyses. Given the essential roles of ZEBs and PAX6 in neural induction, we propose a model by which miR-200 and miR-96 families coordinate to regulate neural induction. * Author for correspondence ( zhang@waisman.wisc.edu...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (1): 147–155.
Published: 1 January 2013
... ) that is transiently expressed in the developing neural plate in a temporal window corresponding to the period of a-lineage neural induction. Using a genetically encoded calcium indicator we observed multiple calcium transients throughout the developing neural plate in wild-type embryos, but not in mutant embryos...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (5): 1034–1044.
Published: 1 March 2012
... The authors declare no competing financial interests. 3 1 2012 © 2012. Neural induction Neural plate Neural border Anterior neural ridge Secondary prosencephalon Forebrain Telencephalon Fate map Neural patterning Cell intercalation Vertical induction Chick...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (4): 575–584.
Published: 15 February 2009
...Sei Kuriyama; Roberto Mayor Syndecan-4 (Syn4) is a heparan sulphate proteoglycan that is able to bind to some growth factors, including FGF, and can control cell migration. Here we describe a new role for Syn4 in neural induction in Xenopus . Syn4 is expressed in dorsal ectoderm and becomes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (21): 3861–3872.
Published: 1 November 2007
...Chenbei Chang; Richard M. Harland Vertebrate neural induction requires inhibition of bone morphogenetic protein (BMP) signaling in the ectoderm. However, whether inhibition of BMP signaling is sufficient to induce neural tissues in vivo remains controversial. Here we have addressed why inhibition...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (18): 3359–3369.
Published: 15 September 2007
... required for neural induction in the mouse. We have analysed the role of BMP signalling in this process. We demonstrate that prior to gastrulation, Bmp2/4 signalling via Bmpr1a maintains epiblast pluripotency and prevents precocious neural differentiation of this tissue, at least in part by maintaining...
Journal Articles
Journal: Development
Development (2007) 134 (16): 2889–2894.
Published: 15 August 2007
... kinase inhibitors. Biochem. J. 351 , 95 -105. Delaune, E., Lemaire, P. and Kodjabachian, L. ( 2005 ). Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition. Development 132 , 299 -310. Eblaghie, M. C., Lunn, J. S., Dickinson, R. J., Munsterberg, A. E., Sanz...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (16): 2895–2902.
Published: 15 August 2007
..., A., Eivers, E. and De Robertis, E. M. ( 2003 ). Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes Dev. 17 , 3023 -3028. Qu, C. K. and Feng, G. S. ( 1998 ). Shp-2 has a positive regulatory role in ES cell differentiation and proliferation. Oncogene...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (16): 3265–3276.
Published: 15 August 2006
... of chordin . * Author for correspondence (e-mail: eweinber@sas.upenn.edu ) 9 6 2006 © 2006. 2006 β-Catenin FGF signaling Dorsal axis formation Neural induction Dorsoventral patterning Anteroposterior patterning Organizer Nodal Chordin Zebrafish FGF signaling...
Journal Articles
Journal: Development
Development (2006) 133 (7): 1299–1309.
Published: 1 April 2006
... posterior, hindbrain and forebrain markers in apparently correct AP order. Wnt/β-catenin signaling is thus not required in the early embryo for either neural induction or for at least some degree of proper AP patterning. A similar conclusion has recently been reached by simultaneous elimination...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (2): 299–310.
Published: 15 January 2005
...Emilie Delaune; Patrick Lemaire; Laurent Kodjabachian Neural induction constitutes the first step in the generation of the vertebrate nervous system from embryonic ectoderm. Work with Xenopus ectodermal explants has suggested that epidermis is induced by BMP signals,whereas neural fates arise...
Journal Articles
Journal: Development
Development (2004) 131 (22): 5671–5681.
Published: 15 November 2004
...Claudia Linker; Claudio D. Stern A dominant molecular explanation for neural induction is the `default model', which proposes that the ectoderm is pre-programmed towards a neural fate, but is normally inhibited by endogenous BMPs. Although there is strong evidence favouring this in Xenopus , data...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3581–3592.
Published: 1 August 2004
... a region of bmp expression, do contribute to the tail spinal cord. Most models suggest that neural induction is dependent upon secreted molecules, notably Bmp antagonists, emanating from the dorsal organiser( Kodjabachian et al., 1999 ; Munoz-Sanjuan and Hemmati-Brivanlou,2002 ); but the presence...
Journal Articles
Journal: Development
Development (2003) 130 (10): 2071–2081.
Published: 15 May 2003
... suggests that EGF-CFC genes can also activate certain cellular responses independently of nodal signaling. Here, we show that FRL-1 , a Xenopus EGF-CFC gene, suppresses BMP signaling to regulate an early step in neural induction. Overexpression of FRL-1 in animal caps induced the early neural markers zic3...
Journal Articles
Journal: Development
Development (2003) 130 (2): 331–342.
Published: 15 January 2003
... for correspondence (e-mail: mmercola@burnham.org ) 10 10 2002 © 2003. 2003 Dlx Neural crest Neural induction Xenopus hairy2a slug snail msx The juxtaposition of presumptive neural plate and epidermis forms a signaling center responsible for the stereotypic pattern...
Journal Articles
Journal: Development
Development (2003) 130 (1): 147–159.
Published: 1 January 2003
... 10 2002 © 2003. 2003 Ciona MEK FGF ERK Ascidian Tunicate Neural patterning Neural induction In chick embryos, FGF signalling is implicated in the earliest inductive events of neural tissue, which occur before the onset of gastrulation( Wilson et al., 2000 ; Streit et al...
Journal Articles
Journal: Development
Development (2002) 129 (23): 5529–5540.
Published: 1 December 2002
...Ignacio Muñoz-Sanjuán; Esther Bell; Curtis R. Altmann; Alin Vonica; Ali H. Brivanlou The earliest decision in vertebrate neural development is the acquisition of a neural identity by embryonic ectodermal cells. The default model for neural induction postulates that neural fate specification...