1-20 of 52
Keywords: Neural development
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development dev.200561.
Published: 28 July 2022
...://www.biologists.com/user-licence-1-1/ Definitive endoderm Directed differentiation Neural development Organoids Pluripotent stem cells Rapid and robust directed differentiation of mouse epiblast stem cells into definitive endoderm and forebrain organoids Daniel Medina-Cano1,2 Emily K. Corrigan1,2 Rachel...
Journal Articles
Journal: Development
Development (2022) 149 (14): dev200049.
Published: 21 July 2022
... neural development. By profiling the genome-wide dynamics of H3K9ac, H3K9cr and H3K18la in combination with ATAC and RNA sequencing, we reveal that these marks are tightly correlated with chromatin state and gene expression, and extensively involved in transcriptome remodeling to promote cell-fate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (12): dev184093.
Published: 22 June 2020
... as a homodimer to dominantly impose neural identity on pluripotent cells. E2A BHLH Neural development Pluripotent Following the establishment of the primary germ layers during gastrulation, the embryonic neural plate is specified from the anterior ectoderm at approximately embryonic day (E)7.5...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (4): dev182204.
Published: 26 February 2020
.... To examine the effect of altered oscillatory dynamics of Hes1, we generated two types of Hes1 knock-in mice, a shortened (type-1) and an elongated (type-2) Hes1 gene, and examined their phenotypes focusing on neural development. Although both mutations affected Hes1 oscillations, the type-1 mutation dampened...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (21): dev183269.
Published: 8 November 2019
... modulates signalling in order to facilitate the differentiation process. Cadherin FGF Neural development Pluripotent Wnt Mouse There is an increasing appreciation that changes in adhesion and morphology help to regulate cell fate changes ( Gilmour et al., 2017 ). The homotypic adhesion...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (12): dev173807.
Published: 27 March 2019
... specification . Neuron   40 , 81 - 95 . 10.1016/j.neuron.2003.08.006 Philippidou , P. and Dasen , J. S. ( 2013 ). Hox genes: choreographers in neural development, architects of circuit organization . Neuron   80 , 12 - 34 . 10.1016/j.neuron.2013.09.020 Preibisch , S...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (2): dev169763.
Published: 29 January 2019
... interference identifies SoxN and Sox102F as key regulators of the morphological properties of a neuronal type of the fruit fly visual system that computes the direction of motion. Neural development Layer specificity Optic lobe Drosophila SoxN Sox102F The formation of neural circuits...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2018) 145 (22): dev172049.
Published: 19 November 2018
... of Biologists on ‘Thinking beyond the dish: taking in vitro neural differentiation to the next level’, highlighting the limitations and potential applications of organoid-based technologies. Neural development Organoids In vitro Neural differentiation Developmental biology aims...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2018) 145 (10): dev151415.
Published: 14 May 2018
... guidance. Axon guidance Guidance cues Neural development Local translation MicroRNA Vesicular transport Neural circuits are the basis of neural function in health and disease, and the faulty assembly or disintegration of these circuits can result in disorders of the nervous system...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2018) 145 (9): dev159426.
Published: 2 May 2018
... with neuronal complexity in Drosophila and vertebrates, highlighting atonal as a platform for understanding proneural gene structure and regulation. bHLH gene Neural development Neurogenesis Neuronal diversity Proneural gene The function of the nervous system relies on a large number...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2018) 145 (3): dev157446.
Published: 2 February 2018
... tyrosine kinase causes larval feeding defects associated with abnormal axon innervation and defective peristalsis of the midgut. Neural development Enteric nervous system Ret signaling GDNF signaling Axon branching Drosophila The RET (rearranged during transfection) receptor tyrosine...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (20): 3744–3754.
Published: 15 October 2017
... throughout the pancreas. A screen of pancreatic extracellular signals identified factors that stimulated islet cell development. These included semaphorin 3a, a guidance cue in neural development without known functions in the pancreas. In the fetal pancreas, peripheral mesenchymal cells expressed Sema3a...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2017) 144 (10): 1807–1819.
Published: 15 May 2017
... junction. GABA synapse Neural circuit Neural development E/I balance Neurons in the brain are organized into circuits, and the activity of these circuits is regulated by the integration of excitatory and inhibitory synaptic inputs. Thus, appropriate numbers and proper positioning...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (7): 1160–1169.
Published: 1 April 2016
... arrest serves a dual role: it prevents progenitor self-renewal and it synchronizes cell division with developmental signals. Neural development Sensory organs Mitosis G2 arrest Cell differentiation The development of a functional nervous system requires precise coordination of self...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (19): 3286–3293.
Published: 1 October 2015
... approaches reveal that Nkx2.2, Nkx6.1 and Olig2 directly repress multiple alternative fates during mammalian neural progenitor fate specification. Transcriptional regulation Fate specification Neural development Mouse Sonic hedgehog (Shh) signaling is crucial for the specification of ventral...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (18): 3138–3150.
Published: 15 September 2015
... cortex Human brain evolution Neural development Neurogenesis Patterning Pluripotent stem cell The mechanisms of human brain development have long been attracting researchers' attention, but they have been challenging to explore because of the inherent difficulty of their experimental study...
Journal Articles
Journal: Development
Development (2015) 142 (18): 3166–3177.
Published: 15 September 2015
..., suggesting that they contribute to establishing regional identity. Cell specification Neural development Neural stem cells MicroRNA MicroRNAs (miRNAs) are small noncoding RNAs that mediate post-transcriptional regulation of gene expression ( Bartel, 2004 ). A single miRNA can have up...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (18): 3178–3187.
Published: 15 September 2015
...-derived cerebral cortex neurons form large-scale functional networks that change over time and mimic those found in the developing cerebral cortex in vivo . Cerebral cortex Networks Neural development Stem cells Human The onset of embryonic synapse formation coincides...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (3): 486–496.
Published: 1 February 2015
... protrusions called invadosomes, which are necessary for axonal growth as motor neurons exit the spinal cord. Axon guidance Pathfinding Neural development Xenopus During development, growth cones guide neurites to their proper synaptic partners by functioning as highly specialized molecular...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (13): 2543–2548.
Published: 1 July 2014
... and reproduction in any medium provided that the original work is properly attributed. Amyloid precursor protein Neural development Axonal outgrowth Synapse formation Alzheimer's disease (AD) is characterized by a progressive degeneration of neurons, which results in cognitive deficiency...