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Keywords: Neural crest cells
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Journal Articles
Journal: Development
Development (2023) 150 (8): dev201289.
Published: 20 April 2023
... fiber growth into the gut is unknown. In vertebrates, CXCR4, a cell-surface receptor for the CXCL12 chemokine, regulates migration of neural crest cells and axon pathfinding. We have employed chimeric tissue recombinations and organ culture assays to study the role of CXCR4 and CXCL12 molecules...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2022) 149 (20): dev201052.
Published: 18 October 2022
...) patterning. Moreover, maturation of the neural tube organoids showed the emergence of multipotent neural crest cells and mature neurons. Single-cell transcriptome analyses revealed the sequence of transcriptional events in the emergence of neural crest cells and neural differentiation. Thanks...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (12): dev200349.
Published: 28 June 2022
... . 10.1074/jbc.M112.349274 Chen , Y. , Wang , Z. , Chen , Y. and Zhang , Y. ( 2019 ). Conditional deletion of Bmp2 in cranial neural crest cells recapitulates Pierre Robin sequence in mice . Cell Tissue Res. 376 , 199 - 210 . 10.1007/s00441-018-2944-5 Claes , P...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (22): dev199825.
Published: 26 November 2021
...Nandor Nagy; Tamas Kovacs; Rhian Stavely; Viktoria Halasy; Adam Soos; Emoke Szocs; Ryo Hotta; Hannah Graham; Allan M. Goldstein ABSTRACT The enteric nervous system (ENS), which is derived from enteric neural crest cells (ENCCs), represents the neuronal innervation of the intestine. Compromised ENCC...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2020) 147 (3): dev185256.
Published: 3 February 2020
... musculoskeletal and connective tissues. We demonstrate that CPM contributes to medial pharyngeal skeletal and connective tissues associated with both branchiomeric and somite-derived neck muscles. CPM and neural crest cells (NCC) make complementary mediolateral contributions to pharyngeal structures...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2016) 143 (7): 1192–1204.
Published: 1 April 2016
... that affects the NNE and neural crest cells. The resulting loss of NNE integrity contributes to an inability of the cranial neural folds to move toward the midline and results in NTD. Further, we identified Esrp1 , Sostdc1 , Fermt1 , Tmprss2 and Lamc2 as novel NNE-expressed genes that are downregulated...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2013) 140 (11): 2247–2251.
Published: 1 June 2013
... no competing financial interests. © 2013. Published by The Company of Biologists Ltd 2013 Neural crest cells Epithelium-to-mesenchyme transition Cell migration Chemotaxis Contact-inhibition of locomotion Cancer Neurocristopathies The neural crest (NC) is a multipotent stem cell...
Journal Articles
Journal: Development
Development (2011) 138 (24): 5403–5414.
Published: 15 December 2011
... ear and CVG. Non-autonomous cell signaling from the hindbrain to the OV is required for inner ear morphogenesis and neurogenesis. In this study, we show that neuroepithelial cells (NECs), including neural crest cells (NCCs), can contribute directly to the OV from the neural tube. Using Wnt1-Cre, Pax3...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (17): 2927–2937.
Published: 1 September 2010
... to further investigate the role of 5-HT2B in embryogenesis, focusing on craniofacial development. By means of gene gain- and loss-of-function approaches and tissue transplantation assays, we demonstrated that 5-HT2B modulates, in a cell-autonomous manner, postmigratory skeletogenic cranial neural crest cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (18): 3195–3203.
Published: 15 September 2009
...Noah R. Druckenbrod; Miles L. Epstein The enteric nervous system (ENS) develops from neural crest cells (NCCs)that enter the foregut and hindgut to become enteric neural-crest-derived cells (ENCCs). When these cells of neural crest origin fail to colonize the terminal hindgut, this aganglionic...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (4): 637–645.
Published: 15 February 2009
...Maryline Minoux; Gregory S. Antonarakis; Marie Kmita; Denis Duboule; Filippo M. Rijli In vertebrates, face and throat structures, such as jaw, hyoid and thyroid cartilages develop from a rostrocaudal metameric series of pharyngeal arches,colonized by cranial neural crest cells (NCCs). Colinear Hox...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (21): 3555–3565.
Published: 1 November 2008
...Yoshiaki Okamura; Yumiko Saga Notch signaling is involved in neurogenesis, including that of the peripheral nervous system as derived from neural crest cells (NCCs). However,it remains unclear which step is regulated by this signaling. To address this question, we took advantage of the Cre-loxP...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (5): 1095–1105.
Published: 1 March 2002
...Jon P. Golding; Monica Dixon; Martin Gassmann Within the developing vertebrate head, neural crest cells (NCCs) migrate from the dorsal surface of the hindbrain into the mesenchyme adjacent to rhombomeres (r)1 plus r2, r4 and r6 in three segregated streams. NCCs do not enter the intervening...