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Keywords: Netrin 1
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Journal Articles
Journal: Development
Development (2023) 150 (22): dev201884.
Published: 22 November 2023
... restricted, stroma-derived signaling molecule, netrin 1 (Ntn1), as a regulator of renal vascular patterning in mice. Stromal progenitor (SP)-specific ablation of Ntn1 ( Ntn1 SPKO ) resulted in smaller kidneys with fewer glomeruli, as well as profound defects of the renal artery and transient blood flow...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (22): dev201886.
Published: 22 November 2023
... is established during kidney development. More specifically, how signals from the kidney influence vessel maturity and patterning remains poorly understood. Netrin 1 (Ntn1) is a secreted ligand that is crucial for vessel and neuronal guidance. Here, we demonstrate that Ntn1 is expressed by Foxd1 + stromal...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2006) 133 (5): 845–853.
Published: 1 March 2006
... the migration and that lot cells are attracted to netrin 1, an axon guidance factor. Furthermore, we demonstrate that mutations in the genes encoding netrin 1 and its functional receptor Dcc lead to inappropriate distribution of lot cells and subsequent partial disruption of LOT projection. These results...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (17): 3321–3330.
Published: 1 September 2001
... 1 and Sema3a in the optic chiasma, and that of Unc5h1 and neuropilin 1 in the optic nerve. Co-culture experiments of the optic nerve with cell clusters expressing guidance cues revealed that the migrating GP cells in the optic nerve were heterogeneous. Netrin 1 repelled a subtype of NG2-positive...