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Keywords: Nephron progenitor
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Journal Articles

Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk

Alexander N. Combes, Belinda Phipson, Kynan T. Lawlor, Aude Dorison, Ralph Patrick, Luke Zappia, Richard P. Harvey, Alicia Oshlack, Melissa H. Little
Journal: Development
Development (2019) 146 (12): dev178673.
https://doi.org/10.1242/dev.178673
Published: 12 June 2019
...Alexander N. Combes; Belinda Phipson; Kynan T. Lawlor; Aude Dorison; Ralph Patrick; Luke Zappia; Richard P. Harvey; Alicia Oshlack; Melissa H. Little; Allon Klein; Barbara Treutlein ABSTRACT Recent advances in the generation of kidney organoids and the culture of primary nephron progenitors from...
View article titled, Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk
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Includes: Supplementary data
Journal Articles

A Sall1-NuRD interaction regulates multipotent nephron progenitors and is required for loop of Henle formation

In collection:
Stem cells & regeneration
Jeannine M. Basta, Lynn Robbins, Darcy R. Denner, Grant R. Kolar, Michael Rauchman
Journal: Development
Development (2017) 144 (17): 3080–3094.
https://doi.org/10.1242/dev.148692
Published: 1 September 2017
... progenitor to renal vesicle are not well understood. Here, we show that Sall1interacts with the nucleosome remodeling and deacetylase complex (NuRD) to inhibit premature differentiation of nephron progenitor cells. Disruption of Sall1-NuRD in vivo in knock-in mice (Δ SRM ) resulted in accelerated...
View article titled, A Sall1-NuRD interaction regulates multipotent <span class="search-highlight">nephron</span> <span class="search-highlight">progenitors</span> and is required for loop of Henle formation
Open the PDF for A Sall1-NuRD interaction regulates multipotent <span class="search-highlight">nephron</span> <span class="search-highlight">progenitors</span> and is required for loop of Henle formation in another window
Includes: Supplementary data
Journal Articles

Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis

Jingyue Xu, Han Liu, Joo-Seop Park, Yu Lan, Rulang Jiang
Journal: Development
Development (2014) 141 (7): 1442–1452.
https://doi.org/10.1242/dev.103283
Published: 1 April 2014
... nephron progenitor cells, whereas canonical Wnt signaling induces nephron differentiation. How Six2 maintains the nephron progenitor cells against Wnt-directed commitment is not well understood, however. We report here that Six2 is required to maintain expression of Osr1, a homolog of the Drosophila odd...
View article titled, Osr1 acts downstream of and interacts synergistically with Six2 to maintain <span class="search-highlight">nephron</span> <span class="search-highlight">progenitor</span> cells during kidney organogenesis
Open the PDF for Osr1 acts downstream of and interacts synergistically with Six2 to maintain <span class="search-highlight">nephron</span> <span class="search-highlight">progenitor</span> cells during kidney organogenesis in another window
Includes: Supplementary data