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Keywords: Nephron progenitor
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Journal Articles
Alexander N. Combes, Belinda Phipson, Kynan T. Lawlor, Aude Dorison, Ralph Patrick, Luke Zappia, Richard P. Harvey, Alicia Oshlack, Melissa H. Little
Journal:
Development
Development (2019) 146 (12): dev178673.
Published: 12 June 2019
...Alexander N. Combes; Belinda Phipson; Kynan T. Lawlor; Aude Dorison; Ralph Patrick; Luke Zappia; Richard P. Harvey; Alicia Oshlack; Melissa H. Little; Allon Klein; Barbara Treutlein ABSTRACT Recent advances in the generation of kidney organoids and the culture of primary nephron progenitors from...
Includes: Supplementary data
Journal Articles
In collection:
Stem cells & regeneration
Journal:
Development
Development (2017) 144 (17): 3080–3094.
Published: 1 September 2017
... progenitor to renal vesicle are not well understood. Here, we show that Sall1interacts with the nucleosome remodeling and deacetylase complex (NuRD) to inhibit premature differentiation of nephron progenitor cells. Disruption of Sall1-NuRD in vivo in knock-in mice (Δ SRM ) resulted in accelerated...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2014) 141 (7): 1442–1452.
Published: 1 April 2014
... nephron progenitor cells, whereas canonical Wnt signaling induces nephron differentiation. How Six2 maintains the nephron progenitor cells against Wnt-directed commitment is not well understood, however. We report here that Six2 is required to maintain expression of Osr1, a homolog of the Drosophila odd...
Includes: Supplementary data