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Keywords: Myosin II
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Journal Articles
Journal: Development
Development (2020) 147 (7): dev179648.
Published: 14 April 2020
.... Endocytic activity gradually reduces as tissue remodeling progresses. This reduced endocytic activity accelerates cell elimination through the regulation of Myosin II subcellular reorganization, junctional E-cadherin levels, and caspase activation. Whereas the increased Myosin II dynamics accelerates cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (17): dev171256.
Published: 6 September 2019
..., suggesting that the junctional network relaxes to accommodate germline growth. At that time, a prominent medial Myosin II network coupled to corrugating adherens junctions develops. Local enrichment of medial Myosin II in main body follicle cells resists germline-derived forces, thus constraining apical...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (13): 2549–2558.
Published: 1 July 2014
... activation of myosin-II, which becomes localized to the apical domains of cells just prior to rosette formation ( Ernst et al., 2012 ; Harding and Nechiporuk, 2012 ). Myosin-II is activated by phosphorylation, which is dependent on both Rho kinase 2a (Rock2a) and the scaffolding molecule Shroom3; loss...
Journal Articles
Journal: Development
Development (2012) 139 (18): 3432–3441.
Published: 15 September 2012
... that the kinases Rok and Drak function redundantly during Myosin II-dependent cell constriction, subsequent multicellular alignment and AJ remodelling. In addition, we show that early multicellular patterning characterized by cell alignment is promoted by the conserved transcription factor Atonal (Ato). Further...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (8): 1385–1394.
Published: 15 April 2010
... and aligns into parallel columns. Live imaging shows that this is accomplished by the shrinkage of select cell interfaces, as three-cell junctions are converted to four-cell junctions. Additionally, we show that non-muscle Myosin II and the polarity proteins Discs large (Dlg) and Bazooka are enriched along...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (8): 1373–1383.
Published: 15 April 2010
... apical circumference remodeling failed or was incomplete in all the mouse mutants affected in hair bundle morphogenesis that we tested. During the normal shape transition, myosin VIIa and myosin II (A and B isoforms) displayed polarized redistributions into and out of the developing lobes, respectively...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (21): 4257–4267.
Published: 1 November 2006
..., Hybridoma Bank), 1:10; mouse anti-GEF64C ( Bashaw et al.,2001 ) 1:50; rabbit anti-DRhoGEF2( Padash Barmchi et al., 2005 )1:1000; rabbit anti-Myosin II heavy chain( Bloor and Kiehart, 2001 )1:500; mouse anti-Rho1 (P1D9) ( Magie et al., 2002 ) 1:50 and Phalloidin Alexa-594 (Molecular Probes) 1:200. All...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (4): 671–681.
Published: 15 February 2003
...Change Tan; Beth Stronach; Norbert Perrimon Myosins are a superfamily of actin-dependent molecular motor proteins,among which the bipolar filament forming myosins II have been the most studied. The activity of smooth muscle/non-muscle myosin II is regulated by phosphorylation of the regulatory...