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Keywords: Myocd
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Journal Articles
Journal: Development
Development (2022) 149 (15): dev200522.
Published: 29 July 2022
... in these precursors exhibit a delayed onset and reduced level of SMC differentiation and peristaltic activity, as well as dilatation of the ureter and renal pelvis (hydroureternephrosis) at birth and at postnatal stages. Molecular profiling revealed a delayed and reduced expression of the myogenic driver gene Myocd...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (4): dev199735.
Published: 17 February 2022
... by a complex of the DNA-binding protein SRF and the transcriptional co-activator MYOCD. The pathways that activate expression of Myocd and of SMC structural genes in mesenchymal progenitors are diverse, reflecting different intrinsic and extrinsic signaling inputs. Taking the ureter as a model, we analyzed...
Includes: Supplementary data