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Keywords: Myocardial migration
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Journal Articles
Journal: Development
Development (2015) 142 (17): 2928–2940.
Published: 1 September 2015
...Ding Ye; Huaping Xie; Bo Hu; Fang Lin Coordination between the endoderm and adjacent cardiac mesoderm is crucial for heart development. We previously showed that myocardial migration is promoted by convergent movement of the endoderm, which itself is controlled by the S1pr2/Gα 13 signaling pathway...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (4): 789–799.
Published: 15 February 2013
... (S1pr2/Mil) is essential for myocardial migration, but the underlying mechanisms remain undefined. Here, we show that suppression of Gα 13 signaling disrupts myocardial migration, leading to the formation of two bilaterally located hearts (cardia bifida). Genetic studies indicate that Gα 13 acts...
Includes: Multimedia, Supplementary data
Journal Articles