1-17 of 17
Keywords: Myelin
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (17): dev200640.
Published: 5 September 2022
... regarding the temporal and molecular control of their division and its impact on myelination. We report that Sil, a spindle pole protein associated with autosomal recessive primary microcephaly, is required for temporal mitotic exit of SCs. In sil -deficient cassiopeia ( csp −/− ) mutants, SCs fail...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (13): dev200597.
Published: 7 July 2022
...Joana Paes de Faria; Raquel S. Vale-Silva; Reinhard Fässler; Hauke B. Werner; João B. Relvas ABSTRACT The extensive morphological changes of oligodendrocytes during axon ensheathment and myelination involve assembly of the Ilk-Parvin-Pinch (IPP) heterotrimeric complex of proteins to relay essential...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (9): dev172502.
Published: 2 May 2019
...Mary Zakaria; Julien Ferent; Ines Hristovska; Yousra Laouarem; Amina Zahaf; Abdelmoumen Kassoussi; Marie-Eve Mayeur; Olivier Pascual; Frederic Charron; Elisabeth Traiffort ABSTRACT Myelination leads to the formation of myelin sheaths surrounding neuronal axons and is crucial for function...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (23): 3983–3995.
Published: 1 December 2015
...Steven A. Goldman; Nicholas J. Kuypers Oligodendrocytes produce myelin, an insulating sheath required for the saltatory conduction of electrical impulses along axons. Oligodendrocyte loss results in demyelination, which leads to impaired neurological function in a broad array of diseases ranging...
Journal Articles
Journal: Development
Development (2015) 142 (23): 4119–4128.
Published: 1 December 2015
...Harwin Sidik; William S. Talbot Precise control of oligodendrocyte migration and development is crucial for myelination of axons in the central nervous system (CNS), but important questions remain unanswered about the mechanisms controlling these processes. In a zebrafish screen for myelination...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (12): 2213–2225.
Published: 15 June 2015
...Bilal E. Kerman; Hyung Joon Kim; Krishnan Padmanabhan; Arianna Mei; Shereen Georges; Matthew S. Joens; James A. J. Fitzpatrick; Roberto Jappelli; Karen J. Chandross; Paul August; Fred H. Gage Myelination in the central nervous system is the process by which oligodendrocytes form myelin sheaths...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (12): 2414–2428.
Published: 15 June 2014
... In the embryonic CNS, development of myelin-forming oligodendrocytes is limited by bone morphogenetic proteins, which constitute one arm of the transforming growth factor-β (Tgfβ) family and signal canonically via Smads 1/5/8. Tgfβ ligands and Activins comprise the other arm and signal via Smads 2/3...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (1): 39–50.
Published: 1 January 2014
... phases of terminal differentiation. Surprisingly, their deletion does not alter precursor characteristics but interferes with proper differentiation. Although a direct influence on myelin gene expression may be part of their function, we provide evidence for another mode of action. SoxB1 proteins promote...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (19): 3600–3612.
Published: 1 October 2012
... of RhoA by Smurf1 is important in this process. In addition, we demonstrate that acute knockdown of Smurf1 in vivo in the developing cerebellar cortex results in impaired axonal growth and migration. Finally, we show that a stabilized form of Smurf1 overrides the inhibition of axon growth by myelin. Taken...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (13): 2299–2307.
Published: 1 July 2012
... in which Olig2 was deleted specifically in NG2 cells. Constitutive deletion of Olig2 in NG2 cells in the neocortex and corpus callosum but not in ventral forebrain caused them to convert their fate into astrocytes, with a concomitant severe reduction in the number of oligodendrocytes and myelin. Deletion...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (21): 4639–4648.
Published: 1 November 2011
...Julie R. Perlin; Mark E. Lush; W. Zac Stephens; Tatjana Piotrowski; William S. Talbot During peripheral nerve development, each segment of a myelinated axon is matched with a single Schwann cell. Tight regulation of Schwann cell movement, proliferation and differentiation is essential to ensure...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (13): 2673–2680.
Published: 1 July 2011
...Kelly R. Monk; Kazuo Oshima; Simone Jörs; Stefan Heller; William S. Talbot In peripheral nerves, Schwann cells form the myelin sheath that insulates axons and allows rapid propagation of action potentials. Although a number of regulators of Schwann cell development are known, the signaling pathways...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (3): 415–426.
Published: 1 February 2009
... for the chemotropic guidance cue netrin 1 and its receptor deleted in colorectal carcinoma (Dcc) in the remodeling of oligodendrocyte processes. Postmigratory, premyelinating oligodendrocytes express Dcc but not netrin 1, whereas mature myelinating oligodendrocytes express both. We demonstrate that netrin 1 promotes...
Journal Articles
Journal: Development
Development (2008) 135 (7): 1271–1281.
Published: 1 April 2008
...Michiya Sugimori; Motoshi Nagao; Carlos M. Parras; Hiroko Nakatani; Mélanie Lebel; François Guillemot; Masato Nakafuku Development of oligodendrocytes, myelin-forming glia in the central nervous system (CNS), proceeds on a protracted schedule. Specification of oligodendrocyte progenitors (OLPs...
Journal Articles
Journal: Development
Development (2008) 135 (1): 145–157.
Published: 1 January 2008
... into astrocytes. The in vivo fate of NG2 glia was examined in mice that were double transgenic for NG2creBAC and the Cre reporter Z/EG. In the double transgenic mice, the Cre reporter EGFP was detected in myelinating oligodendrocytes and in a subpopulation of protoplasmic astrocytes in the gray matter...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (9): 1723–1736.
Published: 1 May 2007
...Holly Colognato; Jason Galvin; Zhen Wang; Jenne Relucio; Tom Nguyen; David Harrison; Peter D. Yurchenco; Charles ffrench-Constant Developmental abnormalities of myelination are observed in the brains of laminin-deficient humans and mice. The mechanisms by which these defects occur remain unknown...
Journal Articles
Journal: Development
Development (2001) 128 (24): 4993–5004.
Published: 15 December 2001
...-A knockout mice. Development 126 , 457 -467. Gow, A., Friedrich, V. L., Jr and Lazzarini, R. A. ( 1992 ). Myelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expression. J. Cell Biol . 119 , 605 -616. Hajihosseini, M., Tham, T. N. and Dubois-Dalcq, M...