... pathway controls both morphognenesis of and cell type specification in mucociliary epithelia: the Xenopus embryonic epidermis and regenerating human airways. Xenopus Human Mucociliary epithelium Multiciliogenesis BMP Notch Epidermis Airway Mucociliary epithelia (MCE...

... of the usual monocilium. Here we report that the transcription factor MYB, which promotes S phase and drives cycling of a variety of progenitor cells, is expressed in postmitotic epithelial cells of the mouse airways and ependyma destined to become MCCs. MYB is expressed early in multiciliogenesis...

... by regulating fluid movement in the intercellular space. Neither their function during organ development nor the molecular mechanisms underlying multiciliogenesis are well understood. Although dysregulation of members of the miR-34 family plays a key role in the progression of various cancers, the physiological...