... Msx transcription factors in foetal meiosis initiation in mammalian germ cells. Upon meiosis initiation, Msx1 and Msx2 genes are strongly expressed in the foetal ovary, possibly stimulated by soluble factors found there: bone morphogenetic proteins Bmp2 and Bmp4, and retinoic acid. Analysis of Msx1...

... and veinules. We previously showed that, in the mouse embryo, Msx1 lacZ and Msx2 lacZ are expressed in mural cells and in a few endothelial cells. To unravel the role of Msx genes in vascular development, we have inactivated the two Msx genes specifically in mural cells by combining the Msx1 lacZ , Msx2 lox...

... of Gsx function disrupts the differentiation of primary interneurons. We demonstrate that, despite their similar expression patterns, the uni-directional system of interactions between homeodomain transcription factors from the Msx, Nkx and Gsx families in the Drosophila neuroectoderm is not conserved...

...., 2007 ). Msx Wnt Cleft lip Lip morphogenesis Lrp6 Retinoic acid Mouse © 2009. © 2009. 2009 13 7 2009 * Author for correspondence( cjzhou@ucdavis.edu ) To address the underlying molecular mechanisms of orofacial defects in Lrp6-KO mice, we examined several factors...

... 31 10 2006 © 2007. 2007 Hair cells Proneural genes Fgf Delta-Notch Pax2-5-8 Foxi1 Dlx Msx no isthmus ( pax2a ) mind bomb Sensory epithelia of the vertebrate inner ear consist of two cell types,hair cells and support cells. Both are produced from a prosensory...

... ; Reddy et al.,2001 ). The following PCR products containing a T7 promoter were used as templates for sense and antisense probe synthesis: Foxn1 (Accession Number NM_008238, nucleotides 1720-2339), and Cre (Accession Number AF169416, nucleotides 2533-3151). Msx, Lef1, Wnt10b and Shh probes were...

... in neural crest specification in chick and Xenopus or zebrafish embryos. * Author for correspondence (e-mail: rmayor@uchile.cl ) 22 10 2003 © 2004. 2004 Xenopus Iroquois Notch signaling BMP Neural crest Msx Hairy2 Delta1 Snail The neural crest is a unique...

... was used for linearization): pSp72- Xslug ( Bgl II,SP6) ( Mayor et al., 1995 ),pSp72-XSnail ( Bgl II, Sp6) ( Essex et al., 1993 ), pKS- XSox2 ( Xba I, T7)( Mizuseki et al., 1998 ),pKS- Msx-1 ( Hox7.1 ) ( Eco RI, T7)( Su et al., 1991 ),pKS- Dll2 ( Dlx3 ) ( Bgl II, T7)( Papalopulu and Kintner,1993 ), pKS...

.... Beauchemin, M. and Savard, P. ( 1992 ). Two Distal-less related homeobox-containing genes expressed in regeneration blastemas of the newt. Dev. Biol . 154 , 55 -65. Bei, M. and Maas, R. ( 1998 ). FGFs and BMP4 induce both Msx-1-independent and Msx-1-dependent signaling pathways in early tooth...

.... Moreover, BMP controls the expression of the MSX transcription factors, and our results suggest that MSX acts downstream of BMP in AER induction. We propose that the BMP signal bifurcates at the level of EN1 and MSX to mediate differentially DV patterning and AER induction, respectively. Our results...

... the activin responsive element. *Author for correspondence (e-mail: nueno@nibb.ac.jp ) 25 4 2001 © 2001. 2001 Head formation Homeobox BMP MSX Anterior endomesoderm nodal FAST Xenopus laevis The establishment of the dorsoventral axis and subsequent pattern formation...

... © 2000 by Company of Biologists 2000 Msx BMP4 Organogenesis Rescue Tooth Mice The development of many vertebrate organs depends on sequential and reciprocal inductive signaling between epithelium and mesenchyme ( Grobstein, 1967 ; Wessells, 1977 ; Saxén, 1977 ; Gurdon, 1992...

... and Dlx2 and we have clarified the relationship between Msx and Dlx gene function in the developing tooth. Dlx1 , Dlx2 double mutants exhibit a lamina stage arrest in maxillary molar tooth development (Thomas B. L., Tucker A. S., Qiu M., Ferguson C. A., Hardcastle Z., Rubenstein J. L. R. and Sharpe P. T...

... and of the Msx family in the dorsal domain. The proliferation and differentiation of Msx -expressing cells in the dorsal precartilaginous domain of the vertebra are stimulated by BMP4, which acts upstream of Msx genes. It has previously been shown that the SHH protein arising from the notochord (and floor plate...

...Deborah J. Phippard; Stephen J. Weber-Hall; Paul T. Sharpe; M. Stuart Naylor; H. Jayatalake; Richard Maas; Ian Woo; Desmond Roberts-Clark; Philippa H. Francis-West; Yi-Hsin Liu; Robert Maxson; Robert E. Hill; Trevor C. Dale ABSTRACT Expression of the Msx-1 and Msx-2 homeobox genes have been shown...