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Keywords: Mouse embryo
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Journal Articles
Journal: Development
Development (2022) 149 (3): dev199655.
Published: 4 February 2022
... tissue interactions at key time points in the mouse embryo. We demonstrate the utility of the approach by providing volumetric data, 3D distribution of three main cellular components (epithelial, mesenchymal and endothelial cells) within the developing pancreas, and quantification of their relative...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (1): dev193789.
Published: 7 January 2021
...Simone Probst; Sagar; Jelena Tosic; Carsten Schwan; Dominic Grün; Sebastian J. Arnold ABSTRACT Anterior mesoderm (AM) and definitive endoderm (DE) progenitors represent the earliest embryonic cell types that are specified during germ layer formation at the primitive streak (PS) of the mouse embryo...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (21): dev187187.
Published: 12 November 2020
..., rather than in control of cell proliferation or cell fate. Hippo pathway TAZ YAP Cartilage Mouse embryo The Hippo signalling pathway was discovered as a potent regulator of organ size in Drosophila , and is conserved in mammals ( Harvey and Tapon, 2007 ; Moya and Halder, 2019 ; Pan...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (10): dev188714.
Published: 26 May 2020
... of the organelle. Although mutations in MRPs have been associated with human diseases, little is known about their role during development. Presented here are the null phenotypes for 21 nuclear-encoded mitochondrial proteins and in-depth characterization of mouse embryos mutant for the Mrp genes Mrpl3 , Mrpl22...
Journal Articles
Journal: Development
Development (2018) 145 (19): dev164319.
Published: 2 October 2018
... molecular markers to identify them. Here, we elucidate the expression pattern of the transcription factor Nkx1-2 in the mouse embryo and show that it identifies axial progenitors throughout body axis elongation, including neuromesodermal progenitors and early neural and mesodermal progenitors. We create...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (8): 1271–1283.
Published: 15 April 2016
... remodelling Epigenetics Lineage specification Mouse embryo Pluripotency SMARCC1 Differentiation involves a cascade of cell fate decisions that progressively limit the potential of a cell to contribute to other lineages. Two cell fate decisions take place in the pre-implantation mouse embryo...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (5): 872–879.
Published: 1 March 2016
... compromises migration of myogenic cells to the limb. Mouse embryo Forelimb bud Myogenic cells Somite-derived endothelial cells Pax3 Foxc1 Foxc2 The failure of myogenic progenitors to migrate into the forelimb does not appear to reflect an obvious deficit in these cells and indeed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (21): 3649–3660.
Published: 1 November 2015
... approaches to constitutively activate the NOTCH pathway in the mouse embryo. Early embryonic development, including the establishment of anterior-posterior polarity, is not perturbed by forced NOTCH activation. By contrast, widespread NOTCH activity in the epiblast triggers dramatic gastrulation defects...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (11): 2349–2359.
Published: 1 June 2014
... organisms such as early post-implantation mouse embryos. We introduce here a microdevice to achieve localised electroporation with high efficiency and reduced cell damage. In silico simulations using a simple electrical model of mouse embryos indicated that a dielectric guide-based design would improve...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (5): 1140–1150.
Published: 1 March 2014
... work is properly attributed. Mouse embryo Trophectoderm Primitive endoderm Embryoid body Endocytosis Maternal diet RhoA Environmental factors around the time of conception including maternal nutrition, health and body condition together with in vitro assisted...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (7): 1583–1593.
Published: 1 April 2013
... D. ( 1995 ). What can be learned from intermediate filament gene regulation in the mouse embryo . Int. J. Dev. Biol. 39 , 443 – 457 . Ertürk A. , Hellal F. , Enes J. , Bradke F. ( 2007 ). Disorganized microtubules underlie the formation of retraction bulbs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (20): 3722–3731.
Published: 15 October 2012
... specification of embryonic blastomeres by sequentially separating the blastomeres in two-cell stage mouse embryos and continuing separation after each cell division throughout pre-implantation development. This procedure eliminates information provided by cell-cell interaction and cell positioning. Gene...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (17): 3248–3256.
Published: 1 September 2012
... of the generated mice will be embryonic lethal; therefore, phenotyping methods tuned to the mouse embryo are needed. Methods that are robust, quantitative, automated and high-throughput are attractive owing to the numbers of mice involved. Three-dimensional (3D) imaging is a useful method for characterizing...
Journal Articles
Journal: Development
Development (2012) 139 (16): 2866–2877.
Published: 15 August 2012
... ). An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo . Development 105 , 733 – 737 . Bernardo A. S. , Faial T. , Gardner L. , Niakan K. K. , Ortmann D. , Senner C. E. , Callery E. M. , Trotter M. W. , Hemberger...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (13): 2288–2298.
Published: 1 July 2012
.... M. , Davies T. ( 1993 ). Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope . Development 118 , 1255 – 1266 . Forlani S. , Lawson K. A. , Deschamps J. ( 2003 ). Acquisition of Hox codes during gastrulation and axial...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (8): 1522–1533.
Published: 15 April 2012
... no competing financial interests. 17 2 2012 © 2012. Dermis Mouse embryo Fibroblasts Hair follicle Wnt β-catenin The dermis contributes to the structural integrity and function of skin. Dermal fibroblasts in the dermis are crucial for hair follicle formation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (2): 423–436.
Published: 15 January 2012
...Marieke Cajal; Kirstie A. Lawson; Bill Hill; Anne Moreau; Jianguo Rao; Allyson Ross; Jérôme Collignon; Anne Camus In the mouse embryo the anterior ectoderm undergoes extensive growth and morphogenesis to form the forebrain and cephalic non-neural ectoderm. We traced descendants of single ectoderm...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (8): 1521–1530.
Published: 15 April 2011
...Daniel W. Stuckey; Melanie Clements; Aida Di-Gregorio; Claire E. Senner; Paul Le Tissier; Shankar Srinivas; Tristan A. Rodriguez During development, the growth of the embryo must be coupled to its patterning to ensure correct and timely morphogenesis. In the mouse embryo, migration of the anterior...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (6): 1093–1097.
Published: 15 March 2011
.... 3A-C ), colocalises with these three receptors in the epicardium and EPDC ( Fig. 3D-F ). In vivo mRNA expression of these molecules in Wt1 GFP -sorted E11.5 epicardial cells was confirmed by qPCR (see Fig. 4 ). Mouse embryo Wilms' tumour suppressor gene Retinoic acid Raldh2 Epicardium...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (20): 3361–3372.
Published: 15 October 2010
...) as an early marker of the PrE lineage and its derivatives in both mouse embryos and ex vivo paradigms of extra-embryonic endoderm (ExEn). By combining live imaging of embryos and embryo-derived stem cells expressing a histone H2B-GFP fusion reporter under the control of Pdgfra regulatory elements...
Includes: Multimedia, Supplementary data