... the response to retinoic acid. Hox genes Transcriptional regulation Shared enhancers Nascent transcription smFISH Retinoic acid signaling Retinoic acid response elements RAREs Neural tube Mouse development Stowers Institute for Medical Research http://dx.doi.org/10.13039/100007795...

... mammalian development and emphasizes their pleiotropic role in cell lineage decisions and early organogenesis. GATA factors Gene redundancy Genetics Lineage specification Mouse development Transcription Human diseases During vertebrate development, the GATA family of transcription...

... in a direction that matches the central hair follicle ( Wu et al., 2012 ; Chang and Nathans, 2013 ). Planar cell polarity Skin Hair follicle Fzd3 Fzd6 Mouse development Summary: The combined signaling intensity of Fzd3 and Fzd6 determines the orientation of hair follicles in developing...

... establishment of the epigenetic states on the X chromosome during embryonic development, which is required for the maintenance of X inactivation at later stages. X inactivation Chromatin Epigenetic modifications Mouse development Female mammals, which have twice as many X-linked genes as males...

.... Kaufman , M. H. ( 1992 ). The Atlas of Mouse Development . London, UK : Academic Press . Kendall , D. G. ( 1989 ). A survey of the statistical theory of shape . Stat. Sci.   4 , 87 - 99 . 10.1214/ss/1177012582 Klingenberg , C. P. ( 1998 ). Heterochrony and allometry...

.../ Summary: Nir controls basal cell proliferation, stratification via the initiation of asymmetric cell division, and cell fate decisions in mouse embryonic epidermis by regulating p63 expression and preventing p53 hyperacetylation. Novel INHAT repressor Mouse development Epidermis p63 Histone...

... consistent with this assignment (not shown). Thus, Ssm1 resides in a 0.5 Mb interval between 147.4 and 147.9 Mb on mouse chromosome 4 ( Fig. 1 A). Fig. 5. HRD -gpt methylation during early mouse development. Gain in HRD- gpt methylation (bisulfite analysis) from E6.5 to E9.5 (B6×D2)F1 mouse...

... development Trophoblast giant cells During early mouse development there are two waves of X-chromosome inactivation (XCI) in XX individuals. Imprinted inactivation of the paternal X chromosome (Xp) initiates in early cleavage stage embryos (from the 4-cell stage) and is carried through...

... cadherins. Here, we demonstrate that Fat family proteins act both synergistically and antagonistically to influence multiple aspects of tissue morphogenesis. We find that Fat1 and Fat4 cooperate during mouse development to control renal tubular elongation, cochlear extension, cranial neural tube formation...

... The authors declare no competing financial interests. 1 4 2011 © 2011. 2011 Aurora kinase B Aurora kinase C Cancer target Mitosis Mouse development Spindle assembly checkpoint Progression through the cell cycle requires the controlled activation of different families...

.... 2008 Axis elongation Convergent extension Definitive endoderm Morphogenesis Mouse development In Xenopus and zebrafish, elongation of the anterior-posterior axis from a spherical early embryo depends on the movement and intercalation of lateral cells towards the midline, a process...

... Spermatogonial stem cells Mouse development Blastocyst Spermatogenesis Transcriptome Male germinal differentiation in mammals comprises two distinct periods delimited by birth (reviewed by Hogan et al., 1994 ). During embryonic development, the primordial germ cells (PGCs) specified in the epiblast...

... 2007 © 2007. 2007 Mouse development Myogenic regulatory factor Limb muscles Myf5 gene control Distal enhancer Muscle-forming cells in trunk, limbs and tail of vertebrate embryos are derived from somites that develop as transient tissue blocks from paraxial mesoderm...

... aspects of myogenesis during mouse development. J. Cell Biol. 128 , 563 -576. Wagschal, A. and Feil, R. ( 2006 ). Genomic imprinting in the placenta. Cytogenet. Genome Res. 113 , 90 -98. Yevtodiyenko, A. and Schmidt, J. ( 2006 ). Dlk1 expression marks developing endothelium and sites...

... and Rubenstein,2002 ; Morasso and Radoja,2005 ). † Author for correspondence (e-mail: morassom@mail.nih.gov ) * Co-senior authors 18 10 2006 © 2007. 2007 Dlx3 p63 Transcription Ectodermal dysplasias Mouse development During embryonic development and organ...

... of vertebral identity during mouse development. Despite a significant overlap in dosage-sensitive homeotic phenotypes and co-repression of a similar set of Hox genes, genetic analysis implicated eed and Bmi1 in parallel pathways, which converge at the level of Hox gene regulation. Whereas EED and BMI1 formed...

... lateral plate mesoderm of a Sufu-/- embryo (D). * Author for correspondence (e-mail: allen.bale@yale.edu ) 2 8 2005 ©2005. 2005 Sufu Suppressor of fused Hedgehog Mouse development Left-right asymmetry Suppressor of fused, like patched, is a negative modulator of Hh...

... ©2005. 2005 Cerebral hypoplasia Heparan sulfate Fibroblast growth factor Sonic hedgehog Mouse development Heparan sulfate (HS) is produced by most mammalian cells as part of membrane and extracellular matrix proteoglycans( Esko and Lindahl, 2001 ). The chain grows...

...-induced limb duplications in mice. Dev. Biol . 176 , 185 -198. Niederreither, K., McCaffery, P., Dräger, U. C., Chambon, P. and Dollé, P. ( 1997 ). Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development...