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Keywords: Mouse blastocyst
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Journal Articles
Journal: Development
Development (2016) 143 (1): 24–34.
Published: 1 January 2016
... stem cell Mouse blastocyst Chimaera Live imaging Pluripotent stem cells provide a valuable system to explore intrinsic and extrinsic requirements for self-renewal in vitro . Murine embryonic stem cells (ESCs) are derived from epiblasts of late blastocysts ( Boroviak et al., 2014 ; Brook...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (21): 4311–4322.
Published: 1 November 2013
... affects the maturation of PrE precursors. Our results suggest that the processes of PrE and epiblast segregation, and cell fate progression are interdependent, and place aPKC as a central player in the segregation of epiblast and PrE progenitors in the mouse blastocyst. ‡ Author for correspondence...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (1): 129–139.
Published: 1 January 2012
... Y. , Pawson T. , Rossant J. ( 2006 ). Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway . Dev. Cell 10 , 615 – 624 . Cheng A. M. , Saxton T. M. , Sakai R. , Kulkarni S. , Mbamalu G...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (18): 3081–3091.
Published: 15 September 2008
... of gene expression in single cells isolated from the mouse blastocyst revealed that expression profiles largely fall within two cohorts: one characterised by PrE-specific genes, the other by EPI-specific genes ( Kurimoto et al., 2006 ). The gene encoding platelet-derived growth factor receptor alpha...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (1985) 88 (1): 303–326.
Published: 1 August 1985
... in developmental potential. These findings challenge earlier conclusions concerning cell lineage and determination in the primitive ectoderm that were based on development in vitro of IS-treated ICMs from giant blastocysts. INTRODUCTION By the onset of implantation the inner cell mass (ICM) of the mouse blastocyst...