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Keywords: Mitosis
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (17): dev200640.
Published: 5 September 2022
... ) . A particularly interesting observation is the difference in the sil deficiency phenotype between retina and Schwann cells. Sil is a ubiquitously expressed protein and is involved in the fundamental process of mitosis but is highly enriched in the nervous system. Neurons might in this case be more sensitive...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (13): dev199944.
Published: 8 July 2022
... fusion, processes that are needed to form the first zygotic nucleus to start a new life. Drosophila meiosis Mitosis Spindle assembly Clathrin Bicaudal D BicD TACC CH-TOG Microtubule transport DeGradFP Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung...
Includes: Supplementary data
Journal Articles
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Reproductive biology
Journal: Development
Development (2022) 149 (7): dev198341.
Published: 14 April 2022
... and aneuploidy in mammalian preimplantation embryos. Aneuploidy BUB1B BUBR1 Cytokinesis Embryo Micronuclei Mitosis National Institutes of Health http://dx.doi.org/10.13039/100000002 5F32HD095550-01 R01HD086073-A1 T32 HD007133 P.E.O. Scholar Award N. L. Tartar...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (8): dev198838.
Published: 16 April 2021
... in adult mouse incisor. Arid1a Mesenchymal stem cells Transit-amplifying cells Cell cycle Mitosis Stem cells reside in a variety of adult tissues, such as the mammalian hematopoietic and nervous systems, intestine and hair follicle ( Morrison et al., 1997 ). During tissue homeostasis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (7): dev183954.
Published: 12 April 2020
... by promoting the basal positioning of nuclei during EMT, an effect that is independent of its catalytic activity. EMT MMP14 Delamination Mitosis Neural crest Polarity Matrix metalloproteinases (MMPs) are widely expressed in cancer and inflammation ( Bonnans et al., 2014 ; Khokha et al...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (4): dev186056.
Published: 21 February 2020
... in prolonged mitosis due to extension of early mitotic stages. This disruption is correlated with depletion of the populations of upper layer neurons in the cortex. In contrast, early cortical neural stem cells proliferate and expand normally in the absence of Sp2. These results indicate a stage-specific...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (2): dev182063.
Published: 15 January 2020
...-p26 silence nanos translation, downregulate a subset of microRNAs involved in germ cell differentiation and suppress ribosomal biogenesis via dMyc to limit germ cell mitosis. We also found that the human ortholog of Wh (WDR4) interacts with TRIM32 in human cells. Our results show that Wh...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (1): dev182295.
Published: 13 January 2020
... in interneuron loss. Our results demonstrate that interneuron development is intimately dependent upon progenitor mitosis duration and uncover a crucial post-transcriptional regulator of interneuron fate relevant for neurodevelopmental pathologies. This article has an associated ‘ The people behind the papers...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2017) 144 (22): 4137–4147.
Published: 15 November 2017
...Tadashi Nakagawa; Teng Zhang; Ryo Kushi; Seiji Nakano; Takahiro Endo; Makiko Nakagawa; Noriko Yanagihara; David Zarkower; Keiko Nakayama The mitosis-meiosis transition is essential for spermatogenesis. Specific and timely downregulation of the transcription factor DMRT1, and consequent induction...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (15): 2767–2779.
Published: 1 August 2016
... of endogenous retroviruses and enable successful progression through meiosis and mitosis. Histone methylation Meiosis Mitosis Pre-implantation development Transcriptional regulation Mouse female germ cells enter meiosis during fetal development and arrest at the dictyate stage of meiotic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (7): 1160–1169.
Published: 1 April 2016
... arrest serves a dual role: it prevents progenitor self-renewal and it synchronizes cell division with developmental signals. Neural development Sensory organs Mitosis G2 arrest Cell differentiation The development of a functional nervous system requires precise coordination of self...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (22): 3921–3932.
Published: 15 November 2015
... Bax or Trp53 (also known as p53 ) rescues the survival of neural progenitors and reduces the growth restriction imposed by Aspm deletion. Our data show that Aspm functions to regulate mitosis and to mitigate DNA damage during CGNP cell division, causes microcephaly through progenitor apoptosis when...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (9): 1843–1856.
Published: 1 May 2013
... G. , Rabeharivelo G. , Frank M. , Cau J. , Delsert C. , Morin N. ( 2010 ). Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis . J. Cell Biol. 190 , 807 – 822 . Bompard G. , Rabeharivelo G. , Cau J. , Abrieu...
Journal Articles
Journal: Development
Development (2012) 139 (21): 3891–3896.
Published: 1 November 2012
... mechanisms and the plethora of factors and mechanisms that could relieve DNA methylation. Competing interests statement The authors declare no competing financial interests. © 2012. 2012 Chromatin Mitosis Epigenetics Gene expression For more than a century it has been known...
Journal Articles
Journal: Development
Development (2012) 139 (3): 503–513.
Published: 1 February 2012
...Leonardo G. Guilgur; Pedro Prudêncio; Tânia Ferreira; Ana Rita Pimenta-Marques; Rui Gonçalo Martinho Epithelial cells mostly orient the spindle along the plane of the epithelium (planar orientation) for mitosis to produce two identical daughter cells. The correct orientation of the spindle relies...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (13): 2661–2672.
Published: 1 July 2011
...Gonzalo Fernández-Miranda; Marianna Trakala; Javier Martín; Beatriz Escobar; Alejandra González; Norbert B. Ghyselinck; Sagrario Ortega; Marta Cañamero; Ignacio Pérez de Castro; Marcos Malumbres Mitosis is controlled by multiple kinases that drive cell cycle progression and prevent chromosome mis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (12): 1953–1963.
Published: 15 June 2010
... the donor nucleus and the recipient cell was not required at the time of transfer, as long as synchrony was reached by the first mitosis. Our findings demonstrate the remarkable flexibility of the reprogramming process and support the importance of nuclear transcriptional regulators in mediating...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (12): 2011–2021.
Published: 15 June 2010
... mitosis are responsible for spindle positioning, leading to precise orientation of the cleavage furrow during ACD in the cells that give rise to the germ lineage in ascidians. * Author for correspondence ( alex.mc-dougall@obs-vlfr.fr ) Competing interests statement The authors declare...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (6): 953–961.
Published: 15 March 2010
... by the widespread failure of replicated chromosomes to disjoin. Surprisingly, rsw4 has neither pronounced cell cycle arrest nor anomalous spindle formation, which occur in other eukaryotes upon loss of separase activity. However, rsw4 roots have disorganized cortical microtubules and accumulate the mitosis-specific...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (3): 449–459.
Published: 1 February 2009
... phenotype. CHK2-mediated mitotic arrest has been previously shown to occur in response to mitotic entry with DNA damage or incompletely replicated DNA. Syncytial embryos lacking NOPO exhibit a shorter interphase during cycle 11, suggesting that they may enter mitosis prior to the completion of DNA...
Includes: Supplementary data