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Keywords: Midbrain-hindbrain boundary
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Journal Articles
Journal: Development
Development (2012) 139 (3): 525–536.
Published: 1 February 2012
...Sebastian Dworkin; Charbel Darido; Smitha R. Georgy; Tomasz Wilanowski; Seema Srivastava; Felix Ellett; Luke Pase; Yanchao Han; Anming Meng; Joan K. Heath; Graham J. Lieschke; Stephen M. Jane The isthmic organiser located at the midbrain-hindbrain boundary (MHB) is the crucial developmental...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (17): 3745–3757.
Published: 1 September 2011
... ) * Present address: MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London W12 0HS, UK Competing interests statement The authors declare no competing financial interests. 17 6 2011 © 2011. Midbrain-hindbrain boundary Organiser Notch signalling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (18): 3137–3148.
Published: 15 September 2008
...Jovica Ninkovic; Christian Stigloher; Christina Lillesaar; Laure Bally-Cuif Neuronal production in the midbrain-hindbrain domain (MH) of the vertebrate embryonic neural tube depends on a progenitor pool called the `intervening zone' (IZ), located at the midbrain-hindbrain boundary. The progressive...
Journal Articles
Journal: Development
Development (2007) 134 (11): 2115–2124.
Published: 1 June 2007
... coherence of the midbrain arc pattern. Finally, HH signaling is required for the integrity and the signaling properties of the boundaries of the midbrain (e.g. the midbrain-hindbrain boundary, the dorsoventral boundary), its perturbations resulting in abnormal cell mixing across `leaky' borders...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (21): 4293–4303.
Published: 1 November 2006
..., P., Tannhauser,B., Kuwada, J. Y., Chitnis, A. B. and Bally-Cuif, L. ( 2003 ). bHLH transcription factor Her5 links patterning to regional inhibition of neurogenesis at the midbrain-hindbrain boundary. Development 130 , 1591 -1604. Geling, A., Plessy, C., Rastegar, S., Strahle, U. and Bally...
Journal Articles
Journal: Development
Development (2005) 132 (14): 3209–3216.
Published: 15 July 2005
... restriction. In order to address segmentation in the midbrain-hindbrain boundary (mhb) region, we have analyzed single cell behavior in the living embryo by acquiring time-lapse movies of the developing mhb region in a transgenic zebrafish line. We traced the movement of hundreds of nuclei, and by matching...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (6): 1261–1272.
Published: 15 March 2005
...Muriel Rhinn; Klaus Lun; Marta Luz; Michaela Werner; Michael Brand The organizing center located at the midbrain-hindbrain boundary (MHB)patterns the midbrain and hindbrain primordia of the neural plate. Studies in several vertebrates showed that the interface between cells expressing Otx and Gbx...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (9): 1993–2006.
Published: 1 May 2004
... neurogenesis in the anlage of the midbrain/hindbrain boundary in the zebrafish neural plate. This involves selective suppression of both neurogenin1 ( ngn1 ) and coe2 mRNA expression in a process that is independent of Notch signalling, and where inhibition of either ngn1 or coe2 expression is sufficient...
Journal Articles
Journal: Development
Development (2003) 130 (18): 4307–4323.
Published: 15 September 2003
...Alexandra Tallafuß; Laure Bally-Cuif The midbrain-hindbrain domain (MH) of the vertebrate embryonic neural tube develops in response to the isthmic organizer (IsO), located at the midbrain-hindbrain boundary (MHB). MH derivatives are largely missing in mutants affected in IsO activity; however...
Journal Articles
Journal: Development
Development (2003) 130 (8): 1591–1604.
Published: 15 April 2003
... a neuron-free zone (`intervening zone', IZ) at the midbrain-hindbrain boundary(MHB). The mechanisms establishing this early pattern of neurogenesis are unknown. We demonstrate that the MHB is globally refractory to neurogenesis,and that forced neurogenesis in this area interferes with the continued...
Journal Articles
Journal: Development
Development (2002) 129 (10): 2317–2327.
Published: 15 May 2002
... of the midbrain-hindbrain boundary (MHB) domain, the neural crest and trigeminal neurons, raising the possibility that iro1 and iro7 have a role in determination of these ectodermal derivatives. A knockdown of iro7 function revealed that iro7 is essential for the determination of neurons in the trigeminal placode...
Journal Articles
Journal: Development
Development (2002) 129 (2): 307–318.
Published: 15 January 2002
...@nt.imp.univie.ac.at ) 22 10 2001 © 2002. 2002 Pax2 Midbrain-hindbrain boundary Enhancer Mouse Pufferfish BAC transgenes The anterior neural plate of the vertebrate embryo is patterned into the forebrain, midbrain and hindbrain under the influence of local organizing centers. One...