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Keywords: MicroRNA
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Journal Articles
Journal: Development
Development (2022) 149 (12): dev199573.
Published: 16 June 2022
... sequencing, we discovered dynamic changes in poly(A) length through deadenylation and re-polyadenylation. Deadenylation appeared to be mediated by microRNAs (miRNAs), and transcripts with shorter poly(A) tails tend to be sequestered into ribonucleoprotein (RNP) granules for translational repression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (9): dev200476.
Published: 3 May 2022
... development is affected by maternal conditions through microRNAs (miRNAs), a group of short noncoding RNAs. Here, we show that miR-129-5p and miR-340-5p suppress cell proliferation in both primary mouse embryonic palatal mesenchymal cells and O9-1 cells, a neural crest cell line, through the regulation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (2): dev199484.
Published: 17 January 2022
...Huanqing Zhang; Pei Zhuang; Ryan M. Welchko; Manhong Dai; Fan Meng; David L. Turner ABSTRACT The mammalian retina contains a complex mixture of different types of neurons. We find that microRNA miR-216b is preferentially expressed in postmitotic retinal amacrine cells in the mouse retina...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (24): dev192948.
Published: 24 December 2020
... defects. Here, we propose the first developmental stage-specific network approach by integrating two crucial regulators, transcription factors (TFs) and microRNAs (miRNAs), to study their co-regulation during craniofacial development. Specifically, we used TFs, miRNAs and non-TF genes to form feed-forward...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2020) 147 (8): dev183723.
Published: 12 April 2020
.../lookup/doi/10.1242/dev.183723.reviewer-comments.pdf References Bartel , D. P. ( 2009 ). MicroRNAs: target recognition and regulatory functions . Cell   136 , 215 - 233 . 10.1016/j.cell.2009.01.002 Bartel , D. P. ( 2018 ). Metazoan microRNAs . Cell   173 , 20 - 51...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (21): dev183111.
Published: 6 November 2019
...Orkan Ilbay; Victor Ambros ABSTRACT MicroRNAs target complementary mRNAs for degradation or translational repression, reducing or preventing protein synthesis. In Caenorhabditis elegans , the transcription factor HBL-1 (Hunchback-like 1) promotes early larval (L2)-stage cell fates, and the let-7...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2019) 146 (17): dev177097.
Published: 2 September 2019
...Daria Bloch; Malikarjuna Rao Puli; Assaf Mosquna; Shaul Yalovsky ABSTRACT Patterning of the root xylem into protoxylem (PX) and metaxylem is regulated by auxin-cytokinin signaling and microRNA miR165a/166b -mediated suppression of genes encoding Class III HOMEODOMAIN LEU-ZIPPER (HD-ZIPIII) proteins...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (7): dev167056.
Published: 4 April 2019
... development by repressing transcription of miRNA genes and contributing to the maintenance of germ plasm integrity during the establishment of the germ cell fate. Germ cell Germ plasm microRNA Transcriptional repression Maternal-to-zygotic transition In many animals, including Drosophila...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2019) 146 (5): dev172932.
Published: 1 March 2019
...Delfina A. Ré; Patricia L. M. Lang; Cristian Yones; Agustin L. Arce; Georgina Stegmayer; Diego Milone; Pablo A. Manavella ABSTRACT Plants use molecular mechanisms to sense temperatures, trigger quick adaptive responses and thereby cope with environmental changes. MicroRNAs (miRNAs) are key...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2018) 145 (24): dev170670.
Published: 17 December 2018
... been extensively studied, little is known about its regulation at the post-transcriptional level. Using the migratory locust Locusta migratoria as a model system, we report here that the microRNAs let-7 and miR-278 bound to the Kr-h1 coding sequence and downregulated its expression. Application of let...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (20): dev161133.
Published: 16 October 2018
...Richard Kaschula; Sofia Pinho; Claudio R. Alonso ABSTRACT Disruptions of normal Hox gene expression can lead to severe morphological defects, revealing a link between the regulation of Hox expression and pattern formation. Here, we explore these links, focusing on the impact of microRNA regulation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (15): dev162594.
Published: 2 August 2018
... evidence that Erk signaling during synovial joint development determines articular cartilage thickness in adult mice. Articular cartilage Kras Erk let-7 Lin28 MicroRNA Osteoarthritis Osteoarthritis (OA) is a highly prevalent skeletal condition among the elderly ( Dieppe and Lohmander...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (13): dev153817.
Published: 6 July 2018
...Moritz Sander; Teresa Eichenlaub; Héctor Herranz ABSTRACT Tissue growth has to be carefully controlled to generate well-functioning organs. MicroRNAs are small non-coding RNAs that modulate the activity of target genes and play a pivotal role in animal development. Understanding the functions...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2018) 145 (10): dev151415.
Published: 14 May 2018
... guidance. Axon guidance Guidance cues Neural development Local translation MicroRNA Vesicular transport Neural circuits are the basis of neural function in health and disease, and the faulty assembly or disintegration of these circuits can result in disorders of the nervous system...
Journal Articles
Journal: Development
Development (2018) 145 (7): dev159053.
Published: 9 April 2018
... target the rho , ru and boss 3′ UTRs, with miR-279/996 loss yielding ectopic R7 photoreceptors and cone cell depletion. Drosophila R7 photoreceptor RTK signaling MicroRNA The Drosophila eye is a choice model system for studying cell fate specification owing to its highly...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2017) 144 (20): 3731–3743.
Published: 15 October 2017
...Alireza Paikari; Cassandra D. Belair; Daniel Saw; Robert Blelloch The vertebrate-specific ESCC microRNA family arises from two genetic loci in mammals: miR-290/miR-371 and miR-302. The miR-302 locus is found broadly among vertebrates, whereas the miR-290/miR-371 locus is unique to eutheria...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2017) 144 (11): 1959–1965.
Published: 1 June 2017
... identity by a microRNA and its APETALA2-like target genes . Plant Cell   15 , 2730 - 2741 . 10.1105/tpc.016238 Boden , S. A. , Cavanagh , C. , Cullis , B. R. , Ramm , K. , Greenwood , J. , Jean Finnegan , E. , Trevaskis , B. and Swain , S. M. ( 2015 ). Ppd-1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (10): 1787–1797.
Published: 15 May 2017
...Elijah J. Spina; Elmer Guzman; Hongjun Zhou; Kenneth S. Kosik; William C. Smith Here we present a parallel study of mRNA and microRNA expression during oral siphon (OS) regeneration in Ciona robusta , and the derived network of their interactions. In the process of identifying 248 mRNAs and 15...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2016) 143 (23): 4474–4485.
Published: 1 December 2016
.../user-licence-1-1/ Drosophila Elav Mei-P26 RNA-binding protein MicroRNA Neuron We confirmed these results by staining mitotic clones of the characterized null allele elav[4] . We used a negatively marked clone strategy in females (as elav resides on the X chromosome), in which...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (22): 4137–4148.
Published: 15 November 2016
...Amir Mizbani; Edlira Luca; Elisabeth J. Rushing; Jan Krützfeldt MicroRNAs (miRNAs) are important regulators of skeletal muscle regeneration, but the underlying mechanisms are still incompletely understood. Here, comparative miRNA sequencing analysis of myogenic progenitor cells (MPs) and non...
Includes: Supplementary data