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Development (2010) 137 (14): 2417–2426.
Published: 15 July 2010
.... In a screen for genes involved in Slit-Robo repulsion, we have identified the Adam family metalloprotease Kuzbanian (Kuz). Kuz does not regulate midline repulsion through cleavage of Slit, nor is Slit cleavage essential for repulsion. Instead, Kuz acts in neurons to regulate repulsion and Kuz can cleave...
Includes: Supplementary data
Development (2006) 133 (20): 4035–4044.
Published: 15 October 2006
... gene encoding a secreted metalloprotease. Ectopic expression of Tlr1 in several tissues of piranha mutants, including hemocytes, completely restores the wild-type innervation pattern, indicating that Tlr1 functions cell non-autonomously. We further show that loss-of-function mutants of related...
Carine Le Goff, Robert P. T. Somerville, Frederic Kesteloot, Kimerly Powell, David E. Birk, Alain C. Colige, Suneel S. Apte
Development (2006) 133 (8): 1587–1596.
Published: 15 April 2006
... for Musculoskeletal Disorders award from NIH (AR050953). References Apte, S. S. ( 2004 ). A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifs: the ADAMTS family. Int. J. Biochem. Cell Biol. 36 , 981 -985. Birk, D. E. and Trelstad, R. L. ( 1986 ). Extracellular...
Development (2004) 131 (23): 6001–6008.
Published: 1 December 2004
...M. Wayne Davis; Andrew J. Birnie; Aubrey C. Chan; Antony P. Page; Erik M. Jorgensen Molting is required for progression between larval stages in the life cycle of nematodes. We have identified four mutant alleles of a Caenorhabditis elegans metalloprotease gene, nas-37 , that cause incomplete...