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Keywords: Meis2
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Journal Articles
Journal: Development
Development (2022) 149 (4): dev200035.
Published: 23 February 2022
...), which arise from a common lateral ganglionic eminence (LGE) progenitor. The molecular mechanisms of cell fate specification of these two neuronal subtypes are incompletely understood. Here, we found that deletion of murine Meis2 , which is highly expressed in the LGE and derivatives, led to a large...
Includes: Supplementary data
Journal Articles
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Neural development
Journal: Development
Development (2021) 148 (10): dev192054.
Published: 25 May 2021
...) In situ hybridization analysis of coronal sections showing Meis2 expression being restricted to 4V ChP epithelium and absent from LV ChP epithelium at E14.5, as observed for Meis1 . Scale bars: 10 µm. (K) Immunostaining of embryonic sagittal sections demonstrating the difference in WNT5A levels...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (19): dev166348.
Published: 11 October 2018
... are functionally linked. Here, we reveal that PcG factors and RA-related signals antagonize each other to polarize Meis2 expression along the PD axis in mouse. Supported by mathematical modeling and simulation, we propose that PcG factors are required to adjust the threshold for RA-related signaling to regulate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (19): 3311–3322.
Published: 1 October 2009
... functional units are, however, poorly understood at present. We show here that the TALE-homeodomain protein Meis2 is expressed in the chick tectal anlage and is both necessary and sufficient for tectal development. Unlike known tectum-inducing genes, the ability of Meis2 to initiate tectal development does...
Includes: Supplementary data