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Keywords: Maternal effect
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Journal Articles
Journal: Development
Development (2021) 148 (19): dev199536.
Published: 13 October 2021
... of the majority of these maternally expressed factors is not fully understood. By exploiting the biallelic editing ability of CRISPR-Cas9, we identify and characterize maternal-effect genes in a single generation, using a maternal crispant technique. We validated the ability to generate biallelic mutations...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (12): dev198010.
Published: 18 June 2021
... genetic screens have provided invaluable insights into the molecular regulation of embryonic development, including the essential contributions of some genes whose products must be provided to the transcriptionally silent early embryo for normal embryogenesis, called maternal-effect genes. However, other...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (4): dev187385.
Published: 26 February 2020
... and chorion formation and elevation. Zebrafish Larp6 Knockout Oocyte Chorion Mass spectrometry Maternal effect La-related proteins (Larps) are a family of evolutionarily conserved RNA-binding proteins with diverse functions ( Maraia et al., 2017 ). Members of the family have been...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (19): dev170266.
Published: 10 July 2019
... Epigenetics Inheritance Reprogramming DNA-methylation Development Trim28/Kap1 Maternal effect KRAB-ZFPs make up the largest subtype of C2H2-type zinc-finger transcription factors with over 300 genes encoded in the mouse genome ( Emerson and Thomas, 2009 ; Kauzlaric et al., 2017 ). While...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (18): 3264–3277.
Published: 15 September 2017
... and cytokine signalling, which impact embryo survival. In addition, a significant proportion of Kdm4a-deficient oocytes displays a poor intrinsic ability to develop into blastocysts. These embryos cannot compete with healthy embryos for implantation in vivo , highlighting Kdm4a as a maternal effect gene. Thus...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (6): 1016–1028.
Published: 15 March 2016
... of these processes. Similarly, the maternal regulation of dorsoventral patterning, and in particular the maternal control of ventral tissue specification, is poorly understood. We identified split top , a recessive maternal-effect zebrafish mutant that disrupts embryonic patterning upstream of endogenous BMP...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (16): 3409–3420.
Published: 15 August 2011
... Gametophytes INCENP Maternal effect Seed development Sexual reproduction Cell cycle regulation WYRD The life cycle of plants alternates between a diploid sporophytic and a haploid gametophytic generation. In flowering plants (angiosperms) gametes are formed by sexually dimorphic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (1): 73–81.
Published: 01 January 2010
...Sebastien Andreuzza; Jing Li; Anne-Elisabeth Guitton; Jean-Emmanuel Faure; Sandrine Casanova; Jin-Sup Park; Yeonhee Choi; Zhong Chen; Frédéric Berger Maternal effects are defined by mutations that affect the next generation when they are maternally inherited. To date, most indepth studies...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (17): 3007–3017.
Published: 01 September 2009
... reticulum. The genes involved in regulating the IP 3 -mediated Ca 2+ release during egg activation remain largely unknown. Here we report on a zebrafish maternal-effect mutant, brom bones , which is defective in the cytosolic Ca 2+ rise and subsequent egg activation events, including cortical granule...
Journal Articles
Journal: Development
Development (2007) 134 (22): 4107–4117.
Published: 15 November 2007
...Quy A. Ngo; James M. Moore; Ramamurthy Baskar; Ueli Grossniklaus; Venkatesan Sundaresan Early seed development of sexually reproducing plants requires both maternal and paternal genomes but is prominently maternally influenced. A novel gametophytic maternal-effect mutant defective in early embryo...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (14): 2757–2770.
Published: 15 July 2006
... program. Zebrafish Spg Pou2 Oct4 Dorsoventral patterning Bmp Epiboly Maternal effect Axis formation During early development, three distinct asymmetries are established in bilaterian embryos, which are precursors to the dorsoventral (DV) and anteroposterior (AP) body axes. Axis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (3): 603–614.
Published: 01 February 2005
..., China Agricultural University, 2 Yuanmingyuan Xilu, Beijing 100094, People's Republic of China 25 11 2004 ©2005. 2005 Arabidopsis thaliana Female gametophyte Embryo sac development Fertilization Maternal effect Transposon insertion mutants The life cycle of plants...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (23): 5947–5958.
Published: 01 December 2004
... for mutations that displayed a maternal rescue effect( Hekimi et al., 1995 ), i.e. homozygous mutant animals issued from a heterozygous mother appear phenotypically wild type (maternally rescued animals are denoted as m + z – throughout the paper). The maternal effect is not strict: heterozygous animals...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (19): 4399–4409.
Published: 01 October 2002
Journal Articles
Journal: Development
Development (2001) 128 (20): 4045–4055.
Published: 15 October 2001
...Claire Bénard; Brent McCright; Yue Zhang; Stephanie Felkai; Bernard Lakowski; Siegfried Hekimi The Caenorhabditis elegans maternal-effect clk genes are involved in the temporal control of development and behavior. We report the genetic and molecular characterization of clk-2 . A temperature...
Journal Articles
Journal: Development
Development (1988) 104 (Supplement): 29–34.
Published: 01 October 1988
... that the establishment of the domain of Kr gene expression is under the control of the maternal effect pattern organizers which act at the poles. The lack of Kr activity causes a gap in the segment pattern of the embryo which is about twice the size of the Kr expression domain and extends posterior to it. This indicates...
Journal Articles
Journal: Development
Development (1985) 89 (Supplement): 53–68.
Published: 01 November 1985
... focused primarily on com- ponents of the centrosome. It appears that amphibian eggs lack a fully functional centrosome. They may, however, contain either a partial centriole (Ramirez & Huff, 1967) or perhaps even a complete but inactive centriole (Manes & Barbieri, Key words: maternal effect, axolotl...