... contributions to zygotes and embryos, yet embryo defective ( emb ) mutants in the Columbia (Col) ecotype display early maternal effects. Here, we show that hybridization of Col with Landsberg erecta (L er ) or Cape Verde Islands (Cvi) ecotypes decreases the maternal effects of emb mutants. Reanalysis of Col/L...

... of the majority of these maternally expressed factors is not fully understood. By exploiting the biallelic editing ability of CRISPR-Cas9, we identify and characterize maternal-effect genes in a single generation, using a maternal crispant technique. We validated the ability to generate biallelic mutations...

... genetic screens have provided invaluable insights into the molecular regulation of embryonic development, including the essential contributions of some genes whose products must be provided to the transcriptionally silent early embryo for normal embryogenesis, called maternal-effect genes. However, other...

... of recessive maternal-effect mutations in the zebrafish using a gynogenesis-based method . Dev. Dyn.   231 , 324 - 335 . 10.1002/dvdy.20145 Pushpa , K. , Kumar , G. A. and Subramaniam , K. ( 2017 ). Translational control of germ cell decisions . Results Probl. Cell Differ.   59 , 175...

... Trim28/Kap1 Maternal effect The inheritance of selective epigenetic information from germline to soma is crucial for organismal development. This epigenetic memory is remarkably maintained during the near-complete erasure of the germ cell epigenomes that establishes the totipotent embryonic...

... and cytokine signalling, which impact embryo survival. In addition, a significant proportion of Kdm4a-deficient oocytes displays a poor intrinsic ability to develop into blastocysts. These embryos cannot compete with healthy embryos for implantation in vivo , highlighting Kdm4a as a maternal effect gene. Thus...

... of these processes. Similarly, the maternal regulation of dorsoventral patterning, and in particular the maternal control of ventral tissue specification, is poorly understood. We identified split top , a recessive maternal-effect zebrafish mutant that disrupts embryonic patterning upstream of endogenous BMP...

... has no effect on oocyte development in Xenopus , zebrafish and Drosophila ( Yamamoto et al., 2008 ; Yabe et al., 2009 ; Resnick et al., 2009 ; Resnick et al., 2006 ), but causes a maternal effect on embryogenesis as observed for wyr . Although homozygous cei male zebrafish are fertile ( Yabe...

...Sebastien Andreuzza; Jing Li; Anne-Elisabeth Guitton; Jean-Emmanuel Faure; Sandrine Casanova; Jin-Sup Park; Yeonhee Choi; Zhong Chen; Frédéric Berger Maternal effects are defined by mutations that affect the next generation when they are maternally inherited. To date, most indepth studies...

... reticulum. The genes involved in regulating the IP 3 -mediated Ca 2+ release during egg activation remain largely unknown. Here we report on a zebrafish maternal-effect mutant, brom bones , which is defective in the cytosolic Ca 2+ rise and subsequent egg activation events, including cortical granule...

...Quy A. Ngo; James M. Moore; Ramamurthy Baskar; Ueli Grossniklaus; Venkatesan Sundaresan Early seed development of sexually reproducing plants requires both maternal and paternal genomes but is prominently maternally influenced. A novel gametophytic maternal-effect mutant defective in early embryo...

... Epiboly Maternal effect Axis formation During early development, three distinct asymmetries are established in bilaterian embryos, which are precursors to the dorsoventral (DV) and anteroposterior (AP) body axes. Axis formation depends largely on maternal and zygotic genes and involves a series...

..., China Agricultural University, 2 Yuanmingyuan Xilu, Beijing 100094, People's Republic of China 25 11 2004 ©2005. 2005 Arabidopsis thaliana Female gametophyte Embryo sac development Fertilization Maternal effect Transposon insertion mutants The life cycle of plants...

... + z – throughout the paper). The maternal effect is not strict: heterozygous animals derived by mating from a homozygous mother are fully wild type. Several aspects of the phenotype of mau-2 mutants can be completely rescued maternally, while others aspects are not. For example, maternally rescued...

... proteasome and eIF3, and evidence from several studies suggests a direct interaction between the complexes or their subunits ( Glickman et al., 1998 ; Kwok et al., 1999 ; Wei et al., 1998 ; Yahalom et al., 2001 ). COP9 signalosome Maternal effect Embryo development Oogenesis Drosophila...

...Claire Bénard; Brent McCright; Yue Zhang; Stephanie Felkai; Bernard Lakowski; Siegfried Hekimi The Caenorhabditis elegans maternal-effect clk genes are involved in the temporal control of development and behavior. We report the genetic and molecular characterization of clk-2 . A temperature...

...Christina Kelly; Alvin J. Chin; Judith L. Leatherman,; David J. Kozlowski and; Eric S. Weinberg ABSTRACT We have identified and characterized a zebrafish recessive maternal effect mutant, ichabod , that results in severe anterior and dorsal defects during early development. The ichabod mutation...

..., so that accumulation of maternally derived gametophytic protein is likely to be responsible for the ‘maternal’ effect. Movie available on-line: http://www.biologists.com/Development/movies/dev0284.html * Author for correspondence (e-mail: patricia.springer@ucr.edu ) 06 04 2000 15 02...

... function in processes other than polarity establishment in the 1-cell embryo. All of the identified par-4 mutations result in a strict maternal-effect lethal phenotype; homozygous mutant worms are viable, but do not produce viable offspring. Thus roles for PAR-4 outside of embryogenesis are likely...

... with germ cells mutant for vir 3 and vir 4 nor did it rescue the lethality of embryos derived from these eggs. Thus, vir has a vital function in female germ cells and a vital maternal effect that are both independent of Sxl ( Table 2 , line III). Table 2. Effects of Sxl M on vir...