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Keywords: Male infertility
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Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2022) 149 (12): dev200489.
Published: 21 June 2022
... proteins, and ACTRT1 in the acroplaxome anchors developing acrosomes to the sperm nucleus. Sperm Perinuclear theca Actin-related protein Detached acrosome Male infertility National Key Research and Development Program of China 2019YFA0802101 Fundamental Research Funds...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (24): dev199922.
Published: 15 December 2021
...-piece thickness in others ( Fig. 6 E). Summary: Analysis of a graded series of KATNB1 loss-of-function models reveals that katanin proteins are required to regulate the vast majority of microtubule-based processes in male germ cell development. Male fertility Male infertility Microtubules...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (23): dev199805.
Published: 7 December 2021
..., and the distribution of intraflagellar transport proteins is disrupted. This study reveals an organ-specific mechanism of axoneme stabilization that is related to male infertility. Minigene splicing assay was carried out as described previously ( Windpassinger et al., 2017 ). C20orf26 (NM_015585.4) minigenes...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (11): dev199216.
Published: 14 June 2021
... 2021 © 2021. Published by The Company of Biologists Ltd 2021 Summary:  RNA sequencing and proteomics analyses of Fsip2 transgenic mouse models reveal insights into the role of Fsip2 in sperm tail and acrosome formation, which may be crucial for fertility. FSIP2 Male infertility...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (21): dev188052.
Published: 15 June 2020
... the epidermal mucociliary epithelium was reduced. Likewise, Cfap206 knockout mice revealed ciliary phenotypes. Electron tomography of immotile knockout mouse sperm flagella indicated a role in radial spoke formation reminiscent of FAP206 function in Tetrahymena . Male infertility, hydrocephalus and impaired...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2016) 143 (24): 4736–4748.
Published: 15 December 2016
... the formation of supernumerary and abnormal axonemes in mouse sperm and leads to male infertility. Cfap157 Ciliogenesis Axoneme Spermiogenesis Male infertility Motile cilia are slender protrusions of the surface of eukaryotic cells. Their core, the axoneme, consists of nine peripheral...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (4): 635–647.
Published: 15 February 2016
..., highlighting key roles for paternal miRNAs/endo-siRNAs. Sperm Small noncoding RNAs Male infertility Embryonic development Assisted reproductive technologies Maternal transcripts In vitro fertilization Epigenetics Spermatozoa (i.e. sperm), as the male gamete, are responsible for not only...
Includes: Supplementary data