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Keywords: MMP2
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Journal Articles
Journal: Development
Development (2008) 135 (17): 2981–2991.
Published: 1 September 2008
... were reduced in E9.5 and E10.5 SM22 α -Cre;R26R;Bmpr1a flox/flox embryos, respectively. Knock-down of BMPR1A by RNA interference in human pulmonary artery SMCs reduced MMP2 and MMP9 activity, attenuated serum-induced proliferation, and impaired PDGF-BB-directed migration. RNA interference of MMP2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (1): 95–109.
Published: 1 January 2008
... required for the execution of several stereotyped motor axon pathfinding decisions. The Drosophila genome contains only two MMP homologs, Mmp1 and Mmp2 . We isolated Mmp1 in a misexpression screen to identify molecules required for motoneuron development. Misexpression of either MMP inhibits the regulated...
Journal Articles
Journal: Development
Development (2005) 132 (15): 3371–3379.
Published: 1 August 2005
... to develop in either experimental or control MBS solutions for another 18-24 hours until they reached stage 40. The experimental solutions were MBS with 5-75 μM MMP2/MMP9 Inhibitor IV (SB-3CT; Chemicon, Temecula, CA), 100-400 μM of a specific peptide gelatinase inhibitor, cyclic CTTHWGFTLC (cyclic CTT...
Journal Articles
Journal: Development
Development (2002) 129 (6): 1487–1496.
Published: 15 March 2002
... in the Müllerian mesenchyme that culminates in apoptosis of the Müllerian duct epithelium. Presently, the paracrine signal(s) used in this developmental event are undefined. We have identified a member of the matrix metalloproteinase gene family, Mmp2 , as one of the first candidate target genes downstream...