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Keywords: MAP kinase
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Journal Articles
Journal: Development
Development (2016) 143 (15): 2732–2740.
Published: 1 August 2016
... signaling MAP kinase RASSF7 Cortical development Fig. 7. A model of DISC1 function in astrogenesis during cortical development. DISC1 activates the RAS/MEK/ERK signaling pathway by direct association with RASSF7 and modulates astrogenesis in the embryonic brain. Fig. 7. A model of DISC1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (3): 431–437.
Published: 1 February 2015
... the activation of the intracellular signaling pathways downstream of LIF in ESCs with different genetic backgrounds. We found that the JAK-Stat3 pathway was dominantly activated in ESCs derived from ‘permissive’ mouse strains (129Sv and C57BL6), whereas the MAP kinase pathway was hyperactivated in ESCs from ‘non...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (13): 2746–2754.
Published: 1 July 2013
.... Published by The Company of Biologists Ltd 2013 EGFR signaling ETS proteins Pointed MAP kinase Eye development pntP2 GFP was generated as follows: a pntP2 cDNA was amplified by PCR and cloned into the Drosophila Gateway vector pTGW (T. Murphy, Carnegie Institution...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (5): 871–882.
Published: 1 March 2012
.... The inability to derive embryonic stem (ES) cell lines in a variety of species suggests divergence between species in the cell signaling pathways involved in early lineage specification. In mouse, segregation of the primitive endoderm lineage from the pluripotent epiblast lineage depends on FGF/MAP kinase...
Journal Articles
Journal: Development
Development (2009) 136 (10): 1687–1696.
Published: 15 May 2009
... Heidelberg, Germany 16 3 2009 © 2009. 2009 Cell cycle Cyclin Fertilization MAP kinase p90Rsk Starfish eggs The transition from oocyte to embryo is essential for initiating embryonic development. A key event in this transition is the start of the embryonic mitotic...
Journal Articles
Journal: Development
Development (2008) 135 (11): 1913–1922.
Published: 1 June 2008
...: Salk Institute for Biological Studies, PBL-M, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA † Present address: INSERM, U784, 46, Rue d'Ulm, 75230 Paris Cedex 05,France 31 3 2008 © 2008. 2008 ESCRT complex MAP kinase HD-PTP (PTPN23) Bro1 domain Photoreceptor...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (15): 2751–2759.
Published: 1 August 2007
... stages before compaction have remained unclear. Here, we show that extracellular signal regulated kinase (ERK) mitogen-activated protein (MAP) kinase function is required for early embryonic cell division before compaction. Our analysis demonstrates that inhibition of ERK activation in late two-cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (21): 4341–4353.
Published: 1 November 2006
...Eric Röttinger; Jenifer Croce; Guy Lhomond; Lydia Besnardeau; Christian Gache; Thierry Lepage Studies in Caenorhabditis elegans and vertebrates have established that the MAP kinase-related protein NLK counteracts Wnt signalling by downregulating the transcription factor TCF. Here, we present...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (11): 2189–2200.
Published: 1 June 2006
...-mail: lepage@obs-vlfr.fr ) * Present address: Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D-01307 Germany 31 3 2006 © 2006. 2006 Endoderm Zebrafish FGF BMP MAP kinase Mesoderm Casanova Bon ERK...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (9): 1823–1830.
Published: 1 May 2006
... calcium, MAP kinase, and DNA synthesis in the sea urchin egg at fertilization. Dev. Biol. 217 , 179 -191. Colledge, W. H., Carlton, M. B. L., Udy, G. B. and Evans, M. J. ( 1994 ). Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs. Nature 370 , 65 -68. Dumont...
Journal Articles
Journal: Development
Development (2006) 133 (8): 1485–1494.
Published: 15 April 2006
.... Choi, K.-W. and Benzer, S. ( 1994 ). Rotation of photoreceptor clusters in the developing Drosophila eye requires the nemo gene. Cell 78 , 125 -136. Cobb, M. H. and Goldsmith, E. J. ( 2000 ). Dimerization in MAP-kinase signaling. Trends Biochem. Sci. 25 , 7 -9. Cooper, M. T...
Journal Articles
Journal: Development
Development (2006) 133 (1): 43–51.
Published: 1 January 2006
... © 2006. 2006 Drosophila moleskin Importin 7 Wing MAP kinase Cell cycle Translocation ERK Ras The activation of MAPK is the final cytoplasmic event in the Ras signal transduction cascade, and alterations in the Ras/MAPK pathway are associated with ∼25...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (14): 3175–3184.
Published: 15 July 2005
... of the intestinal nuclei is unchanged in the sma-5 mutant. The sma-5 gene is expressed in intestine,excretory cell and hypodermis, and encodes homologs of a mammalian MAP kinase BMK1/ERK5/MAPK7, which was reported to control cell cycle and cell proliferation. Expression of the sma-5 gene in hypodermis is important...
Journal Articles
Journal: Development
Development (2003) 130 (19): 4581–4586.
Published: 1 October 2003
... or MII arrest, even when fertilization does not occur. Here we show that MI arrest of starfish oocytes occurs in the ovary after germinal vesicle breakdown. This arrest is maintained both by the Mos/MEK/MAP kinase pathway and the blockage of an increase of intracellular pH in the ovary before spawning...
Journal Articles
Journal: Development
Development (2003) 130 (16): 3703–3714.
Published: 15 August 2003
... dissected immediately, then kept at 25°C with dissections at 1, 2, 4, 6 and 8 hours. The HS:MG and HS:NMG experiments were carried out as follows: 1 with hour at 37°C then 2 hours at 25°C. Fig. 5. MAP kinase-Gal4/Vp16 fusion protein expression suppresses the phenotype of a MAP kinase...
Journal Articles
Journal: Development
Development (2001) 128 (21): 4329–4338.
Published: 1 November 2001
..., but integration is likely to be achieved at least partly by cytoplasmic signal transduction networks. Work in other systems ( Drosophila tracheae, MDCK models) suggests that the mitogen-activated protein (MAP) kinase pathway might be important to epithelial branching. We have investigated the role of the MAP...