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Keywords: M lineage
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Journal Articles
Journal: Development
Development (2011) 138 (6): 1033–1043.
Published: 15 March 2011
... of these processes could lead to disease, including cancer. We have examined the function of the sole C. elegans SoxC protein, SEM-2, in the M lineage, which produces the postembryonic mesoderm. We found that SEM-2/SoxC is both necessary and sufficient to promote a proliferating blast cell fate, the sex myoblast...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (14): 2375–2384.
Published: 15 July 2010
... DRAGON DRAG-1 Sma/Mab signaling Co-receptor Body size Mesoderm M lineage C. elegans Bone morphogenetic proteins (BMPs) belong to the transforming growth factor β (TGFβ) superfamily of ligands and the BMP signaling pathway plays roles in multiple developmental and homeostatic processes...
Journal Articles
Journal: Development
Development (2010) 137 (9): 1451–1460.
Published: 1 May 2010
..., the inability of LET-381, CEH-34 and EYA-1 to transform ventral M lineage cells to CCs suggests that other pan-dorsal or pan-ventral factor(s) must also be under the control of the dorsoventral asymmetry pathways. Additionally, the inability of forced expression of LET-381 on its own to induce ceh-34...
Journal Articles
Journal: Development
Development (2007) 134 (1): 19–29.
Published: 1 January 2007
.... We show that FOZI-1 shares the same expression pattern as CeMyoD in the postembryonic mesodermal lineage, the M lineage, and that fozi-1 -null mutants exhibit similar M lineage-null defects to those found in animals lacking CeMyoD in the M lineage (e.g. loss of a fraction of M lineage-derived BWMs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (15): 2887–2896.
Published: 1 August 2006
... as a downstream component to mediate the Sma/Mab TGFβ signaling pathway in these processes. We have discovered a new role for SMA-9 in dorsoventral patterning of the C. elegans post-embryonic mesoderm, the M lineage. In addition to a small body size, sma-9 mutant animals exhibit a dorsal-to-ventral fate...
Journal Articles
Journal: Development
Development (2004) 131 (21): 5381–5392.
Published: 1 November 2004
... of the myogenic regulatory gene MyoD1. Mol. Cell. Biol. 9 , 3576 -3579. * Author for correspondence (e-mail: michael.stern@yale.edu ) 31 8 2004 © 2004. 2004 FGF receptor EGL-15 PI3 kinase Signal transduction Muscle differentiation M lineage Myoblast SM Sex muscles...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3395–3404.
Published: 15 September 2001
... several differences at the cellular and molecular levels during vulval formation. For example, the mesoblast M participates in lateral inhibition, a process that influences the fate of two vulval precursor cells. Here, we describe the M lineage in Pristionchus and show that both the dorsal and ventral M...