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Keywords: Limb outgrowth
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Journal Articles
Journal: Development
Development (2007) 134 (1): 85–92.
Published: 1 January 2007
... does not impair limb outgrowth. Furthermore, we distinguish two distinct phases of limb development: a Tbx5 -dependent limb initiation phase, followed by a Tbx5 -independent limb outgrowth phase. In humans, mutations in the T-box transcription factor TBX5 are associated with the dominant disorder Holt...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (22): 5471–5479.
Published: 15 November 2003
...Marat Gorivodsky; Peter Lonai The epithelial b variant of Fgfr2 is active in the entire surface ectoderm of the early embryo, and later in the limb ectoderm and AER,where it is required for limb outgrowth. As limb buds do not form in the absence of Fgfr2, we used chimera analysis to investigate...