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Development (2006) 133 (4): 611–619.
Published: 15 February 2006
...Patrick Narbonne; Richard Roy In C. elegans , reduced insulin-like signalling induces developmental quiescence, reproductive delay and lifespan extension. We show here that the C. elegans orthologues of LKB1 and AMPK cooperate during conditions of reduced insulin-like signalling to establish cell...
Development (2003) 130 (6): 1089–1099.
Published: 15 March 2003
... are grossly normal in morphology and development, grow longer to be almost twice as big,and have weak egg-laying defects and extended lifespan. All the four mutants have a mutation in the egl-4 gene. We show that the egl-4 gene encodes cGMP-dependent protein kinases. egl-4 promoter::gfp fusion genes...
Development (2001) 128 (20): 4045–4055.
Published: 15 October 2001
... of gene expression. ¶Author for correspondence (e-mail: Siegfried.Hekimi@mcgill.ca ) 20 7 2001 © 2001. 2001 clk-2 TEL2 Caenorhabditis elegans Maternal effect Telomere length Lifespan The development of sexually reproducing organisms is affected by their parents...